Dexamethasone suppression test

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The dexamethasone suppression test is designed to and differentiate among the various types of [http://worldselectshop.com/?id=9361 syndrome] and other hypercortisol states. [1]

is an exogenous steroid that provides negative feedback to the [http://worldselectshop.com/?id=9361 to suppress the secretion of [http://worldselectshop.com/?id=9361 This steroid is unable to pass the [http://worldselectshop.com/?id=9361 brain barrier] which allows this test to assess a specific part of the axis].

The test is given at low and high doses of Dexamethasone and the levels of [http://worldselectshop.com/?id=9361 are measured to obtain the results.[2] A normal result is decrease in cortisol levels upon administration of low-dose dexamethasone. Results indicative of Cushing's disease involve no change in cortisol on low-dose dexamethasone, but inhibition of cortisol on high-dose dexamethasone. If the cortisol levels are unchanged by low and high-dose dexamethasone then a cortisol secreting adrenocortical tumor is suspected or an ectopic ACTH syndrome.

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