Hodgkin's lymphoma x ray findings
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sowminya Arikapudi, M.B,B.S. [2]
Overview
Chest, spine, pelvic, and long bone x ray may be helpful in the diagnosis of Hodgkin's lymphoma.
X ray Findings
Chest, spine, pelvic, and long bone x ray may be helpful in the diagnosis of Hodgkin's lymphoma.[1] [2]
Chest x ray
- Pulmonary involvement usually indicates stage IV Hodgkin's lymphoma
- The mediastinal mass ratio can be determined by chest X-ray. A mediastinal mass ratio of greater than 0.33 is consistent with bulky disease.
- The following findings on chest x ray may be suggestive of Hodgkin's lymphoma:
- Masses
- Mass-like consolidation
- Diffuse interstitial thickening
- Sternum may be involved
- Ribs may be osteolytic and expansile
- Bilateral involvement is seen in ~4% of cases
- Mediastinal nodal involvement (Primary disease)
- Pulmonary parenchymal involvement (Recurrent disease)
- Peri bronchial infiltration may sometimes be observed
-
Chest x-ray demonstrates widening of the mediastinal outlines and widening of the right para tracheal stripe.[3]
-
Lateral projection confirms predominantly anterior mediastinal mass.[3]
Spine x ray
- Erosion of anterior or anterolateral aspect of the vertebral bodies is a classic finding in Hodgkin's lymphoma , caused by enlarged para vertebral lymph nodes
- Nodular sclerosing Hodgkin's lymphoma shows diffusely increased density with our without anterior erosion; vertebral body height is unaffected
- Single, dense vertebra (ivory vertebra) in adults
- Intervertebral disc spaces are generally unaffected by the disease
Pelvic x ray
- Mixed or sclerosing type predominates
Long bones x ray
- Frequently lytic, extending along the long axis of bone through the medullary cavity with endosteal scalloping of the cortex
References
- ↑ Hodgkin lymphoma. Dr Amir Rezaee and Dr Yuranga Weerakkody et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/hodgkin-lymphoma-pulmonary-manifestations
- ↑ Hodgkin lymphoma. Dr Henry Knipe and Asma J. Q. et al. Radiopaedia.org 2015. http://radiopaedia.org/articles/hodgkin-lymphoma-musculoskeletal-manifestations
- ↑ 3.0 3.1 Image courtesy of Dr Frank Gaillard Radiopaedia(original file ‘’here’’).Creative Commons BY-SA-NC