Chagas disease surgery
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Overview
Surgery is not indicated in the treatment of Chagas disease.
Surgery
Heart transplantation is not considered a contraindication for heart transplantation.
Despite the risk of T cruzi reactivation after transplantation and immunosuppression, universal “prophylactic” antitrypanosomal therapy is not recommended. Quantitative T cruzi PCR provides sufficient sensitivity to detect a reactivation before complications such as allograft dysfunction develop. Benznidazole has been the drug of choice for the treatment of T cruzi reactivations. Because treatment does not result in a cure of chronic T cruzi infection, patients remain vulnerable to new episodes of reactivation, and lifelong T cruzi monitoring is required.