Oligodendroglioma CT

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[3]Sujit Routray, M.D. [4]

Overview

Head CT scan may be helpful in the diagnosis of oligodendroglioma. Findings on CT scan suggestive of oligodendroglioma are round or oval, marginated, hypo- to isodense mass with hemorrhage, calcification, and ill-defined enhancement following intravenous contrast administration.

CT

  • Head CT scan may be helpful in the diagnosis of oligodendroglioma
  • Findings on CT scan suggestive of oligodendroglioma are listed below:[1][2][3][4][5]
    • Round or oval, sharply marginated mass involving the cortex or subcortical white matter
    • Hypodense to isodense mass
    • Hemorrhage
    • Overlying skull may show pressure erosion
    • Calcification (70-90%)
      • Located centrally or peripherally
      • May be ribbon-like
    • Ill-defined enhancement (50%) following intravenous contrast administration
    • Marked ventricular enlargement suggestive of hydrocephalus
Oligodendroglioma CT characteristics
CT type Tumor characteristics on CT
Non-contrast CT
  • Tumors are of mixed density i.e. from hypodense to isodense
  • High-attenuation areas within the tumor are due to:
    • Calcification most likely(70-90% of oligodendrogliomas are calcified), which can be located centrally, peripherally or they can be ribbon-like
    • Hemorrhage (less commonly)
  • Overlying skull may show pressure remodelling
Post-contrast CT
  • Approximately 50% of oligodendrogliomas enhance with degree of enhancement being extremely variable, ranging from:
    • No enhancement to
    • Strikingly vivid enhancement
Heterogeneous region of contrast enhancement, edema, and mass effect is present in the left frontal lobe.Source: Dr. Frank Gaillard. Radiopaedia
Right temporal hypodense space occupying lesion which contains internal central calcifications.Source: Dr. Henry Knipe and Dr Frank Gaillard et al.. Radiopaedia
Oligodendroglioma that is highly calcified. [1]

References

  1. Radiographic features of oligodendroglioma. Dr Henry Knipe and Dr Frank Gaillard et al. http://radiopaedia.org/articles/oligodendroglioma
  2. Stark AM, Hugo HH, Mehdorn HM, Knerlich-Lukoschus F (2009). "Acute Hydrocephalus due to Secondary Leptomeningeal Dissemination of an Anaplastic Oligodendroglioma". Case Rep Med. 2009: 370901. doi:10.1155/2009/370901. PMC 2797365. PMID 20052406.
  3. Image courtesy of Dr. Frank Gaillard. Radiopaedia (original file here). Creative Commons BY-SA-NC
  4. Image courtesy of Dr. Henry Knipe and Dr Frank Gaillard et al.. Radiopaedia (original file here). Creative Commons BY-SA-NC
  5. Oligodendrogliomas. SurgWiki 2015. http://www.surgwiki.com/wiki/Intracranial_tumours,_infection_and_aneurysms#Oligodendroglioma

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