Hemophilia MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

MRI may be helpful in the diagnosis of hemophilia. Findings on MRI suggestive of hemophilic arthropathy include effusion, synovial hyperplasia, erosion, subchondral cyst, cartilage loss, osteonecrosis, fibrocartilage tear, ligament tear, loose body.

MRI

The additive European MRI scoring system

Type of change	Score
Subchondral cysts Present in at least one bone Present in at least two bones More than three cysts in at least one bone More than three cysts in at least two bones Largest size > 4 mm in at least one bone Largest size > 4 mm in at least two bones	1 1 1 1 1 1
Irregularity/erosion of subchondral cortex Present in at least one bone Present in at least two bones Involves more than half of joint surface in at least one bone Involves more than half of joint surface in at least two bones	1 1 1 1
Chondral destruction Present in at least one bone Present in at least two bones Full-thickness defect in at least one bone Full-thickness defect in at least two bones Full-thickness defect involves more than one-third of joint surface in at least one bone Full-thickness defect involves more than one-third of joint surface in at least two bones	1 1 1 1 1 1
Effusion/hemarthrosis	Absent = 0 Equivocal = 1 Small = 2 Moderate = 3 Large = 4
Synovial hypertrophy	Absent = 0 Equivocal = 1 Small = 2 Moderate = 3 Large = 4
Hemosiderin	Absent = 0 Equivocal = 1 Small = 2 Moderate = 3 Large = 4