Henoch-Schönlein purpura causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The common causes of Henoch-Schönlein purpura (HSP) are infections, medications, hypersesitivity, vaccinations, genetics etc.

Causes

  • The causes of the HSP is as follows:[1][2][3][4][5][6]
  • The exact cause of HSP is not clear.
  • Common causes
    • Infections-
    • Medications
    • Hypersesitivity
    • Vaccinations- certain vaccines can cause HSP such as Typhoid, HBV, Measles, Yellow fever, and Cholera.
  • Rare causes
    • Genetics- very rarely HSP can occur in twins and within the family
    • Other triggers Certain drugs, bacteria, insect bites, viral infections, food, cold weather, and trauma may also cause HSP.
  • In HSP, the antibodies are directed against the blood vessels causing vasculitis, bleeding into the skin leading to a subsequent skin rash.
  • Allergic reaction to foods may cause HSP.
  • Very rarely HSP can occur in twins and within the family.

Causes by Organ System

Cardiovascular No underlying causes
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect Cytarabine , Deferiprone, Ethacrynic Acid, Oxytetracycline
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic No underlying causes
Genetic No underlying causes
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic No underlying causes
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic No underlying causes
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary No underlying causes
Renal/Electrolyte No underlying causes
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous No underlying causes

Causes in Alphabetical Order

References

  1. Davin JC, Coppo R (October 2014). "Henoch-Schönlein purpura nephritis in children". Nat Rev Nephrol. 10 (10): 563–73. doi:10.1038/nrneph.2014.126. PMID 25072122.
  2. Micheletti RG, Werth VP (2015). "Small vessel vasculitis of the skin". Rheum. Dis. Clin. North Am. 41 (1): 21–32, vii. doi:10.1016/j.rdc.2014.09.006. PMID 25399937.
  3. Zhdanova LV, Patrushev LI, Dolgikh VV, Bimbaev AB, Khoĭkova O (2014). "[The contribution of genes polymorphism of thrombophilia in clinical variability of hemorrhagic vasculitis]". Vestn. Akad. Med. Nauk SSSR (in Russian) (3–4): 61–4. PMID 25306598. Vancouver style error: initials (help)
  4. Rigante D, Castellazzi L, Bosco A, Esposito S (August 2013). "Is there a crossroad between infections, genetics, and Henoch-Schönlein purpura?". Autoimmun Rev. 12 (10): 1016–21. doi:10.1016/j.autrev.2013.04.003. PMID 23684700.
  5. Audemard-Verger A, Pillebout E, Guillevin L, Thervet E, Terrier B (July 2015). "IgA vasculitis (Henoch-Shönlein purpura) in adults: Diagnostic and therapeutic aspects". Autoimmun Rev. 14 (7): 579–85. doi:10.1016/j.autrev.2015.02.003. PMID 25688001.
  6. Pillebout E, Niaudet P (March 2008). "[Henoch-Schönlein purpura]". Rev Prat (in French). 58 (5): 507–11. PMID 18524107.


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