SGSM2

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Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

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RefSeq (protein)

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Location (UCSC)n/an/a
PubMed searchn/an/a
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View/Edit Human

Small G protein signaling modulator 2 is a protein that in humans is encoded by the SGSM2 gene.[1][2]

Clinical relevance

In a recent genome-wide association study, this gene has been associated with fasting glucose traits, type 2 diabetes and obesity.[3]

References

  1. Yang, H; et al. (2007). "Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway". Genomics. 90 (2): 249–260. doi:10.1016/j.ygeno.2007.03.013. PMID 17509819.
  2. "Entrez Gene: small G protein signaling modulator 2".
  3. Strawbridge, RJ; et al. (2011-08-26). "Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes". Diabetes. 60 (10): 2624–34. doi:10.2337/db11-0415. PMC 3178302. PMID 21873549.

Further reading