Achalasia epidemiology and demographics

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]

Overview

The incidence of Achalasia is approximately ~ 1 per 100,000. There is no predilection to any age and has the same prevalence in both whites and non-whites.

Epidemiology and Demographics

Incidence and Prevalence

  • Achalasia is a rare disease, with an incidence of ~ 1 case per 100,000 per year in adults and a prevalence of 8-10 cases per 100,000.[1][2][3]

Age

  • Most commonly, achalasia is diagnosed between 25 and 60 years old, mean age of diagnosis being > 50 years.[4]

Gender

  • Achalasia has no predilection to any age.[4][3]

Race

  • Achalasia has the same prevalence in both whites and non-whites.[5]

References

  1. Sadowski, DC.; Ackah, F.; Jiang, B.; Svenson, LW. (2010). "Achalasia: incidence, prevalence and survival. A population-based study". Neurogastroenterol Motil. 22 (9): e256–61. doi:10.1111/j.1365-2982.2010.01511.x. PMID 20465592. Unknown parameter |month= ignored (help)
  2. Gennaro N, Portale G, Gallo C, Rocchietto S, Caruso V, Costantini M; et al. (2011). "Esophageal achalasia in the Veneto region: epidemiology and treatment. Epidemiology and treatment of achalasia". J Gastrointest Surg. 15 (3): 423–8. doi:10.1007/s11605-010-1392-7. PMID 21116729.
  3. 3.0 3.1 Birgisson S, Richter JE (2007). "Achalasia in Iceland, 1952-2002: an epidemiologic study". Dig Dis Sci. 52 (8): 1855–60. doi:10.1007/s10620-006-9286-y. PMID 17420933.
  4. 4.0 4.1 Sadowski DC, Ackah F, Jiang B, Svenson LW (2010). "Achalasia: incidence, prevalence and survival. A population-based study". Neurogastroenterol Motil. 22 (9): e256–61. doi:10.1111/j.1365-2982.2010.01511.x. PMID 20465592.
  5. Enestvedt BK, Williams JL, Sonnenberg A (2011). "Epidemiology and practice patterns of achalasia in a large multi-centre database". Aliment. Pharmacol. Ther. 33 (11): 1209–14. doi:10.1111/j.1365-2036.2011.04655.x. PMC 3857989. PMID 21480936.

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