Riedel's thyroiditis medical therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
Pharmacologic medical therapies for Riedel's thyroiditis include corticosteroids, tamoxifen, and mycophenolate mofetil.[1]
Medical Therapy
- Pharmacologic medical therapies for Riedel's thyroiditis include Corticosteroids and tamoxifen.
- Mycophenolate mofetil is also used in combination with corticosteroids.
Treatment regimen for Riedel's thyroiditis
As is a Riedel's thyroiditis rare disease the effectiveness of therapy and dosages have not yet been assessed. As a result, dosage regimens and duration of therapy cannot be defined. The current recommendations are based on the clinical manifestations, associated conditions, and the response to treatment.
- Adult
- Preferred regimen (1): Prednisone 15-60mg PO q24h for 6 months to 2 years
- Preferred regimen (2): Prednisone 500 mg PO q24h for 6 months to 2 years
- Alternative regimen (1): Tamoxifen 10-20 mg PO q24h for 6 months to 2 years
- Alternative regimen (1): Mycophenolate mofetil 1 g PO q12h for 6 months to 2 years
- Pediatric
- Preferred regimen (1): Prednisone 15-60mg PO q24h for 6 months to 2 years
- Preferred regimen (2): Prednisone 500 mg PO q24h for 6 months to 2 years
References
- ↑ Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518. Unknown parameter
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