Zollinger-Ellison syndrome ultrasound
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Mohamad Alkateb, MBBCh [2]
Overview
Abdominal ultrasound may be helpful in the diagnosis of Zollinger-Ellison syndrome caused by gastrinoma.[1]. Ultrasonography can detect gastrinomas in 30%. Endoscopic ultrasonography (EUS) is a highly sensitive and specific procedure for the localization of pancreatic endocrine tumors and duodenal as well as pancreatic gastrinomas.
Abdominal Ultrasound
- Ultrasonography can detect gastrinomas in 30% of cases and the detection rates are better for lesions greater than 3 cm in diameter and are poor for lesions smaller than 1 cm. [2]
- Endoscopic ultrasonography (EUS) is a highly sensitive and specific procedure for the localization of pancreatic endocrine tumors and should be considered for the preoperative localization of such tumors once the clinical and laboratory diagnosis has been established. [3]
- When a gastrinoma is suspected, endoscopy or EUS should also be performed to identify duodenal as well as pancreatic gastrinomas, especially when multiple lesions are suspected as in MEN 1. [4] [5]
References
- ↑ Harvey, Adrian; Pasieka, Janice L.; Al-Bisher, Hassan; Dixon, Elijah (2012). "Primary Hepatic Gastrinoma Causing Zollinger-Ellison Syndrome: A Rare and Challenging Diagnosis". Cancers. 4 (4): 130–140. doi:10.3390/cancers4010130. ISSN 2072-6694.
- ↑ London JF, Shawker TH, Doppman JL, Frucht HH, Vinayek R, Stark HA; et al. (1991). "Zollinger-Ellison syndrome: prospective assessment of abdominal US in the localization of gastrinomas". Radiology. 178 (3): 763–7. doi:10.1148/radiology.178.3.1994415. PMID 1994415.
- ↑ Rösch T, Lightdale CJ, Botet JF, Boyce GA, Sivak MV, Yasuda K; et al. (1992). "Localization of pancreatic endocrine tumors by endoscopic ultrasonography". N Engl J Med. 326 (26): 1721–6. doi:10.1056/NEJM199206253262601. PMID 1317506.
- ↑ Tomassetti P, Migliori M, Lalli S, Campana D, Tomassetti V, Corinaldesi R (2001). "Epidemiology, clinical features and diagnosis of gastroenteropancreatic endocrine tumours". Ann Oncol. 12 Suppl 2: S95–9. PMID 11762360.
- ↑ Jensen RT (1996). "Gastrointestinal endocrine tumours. Gastrinoma". Baillieres Clin Gastroenterol. 10 (4): 603–43. PMID 9113315.