Smoking pathophysiology

Smoking Microchapters
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Case #1

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Pathophysiology

Genetics

• CYP2A6 is the gene coding for enzymes that metabolize nicotine. Polymorphisms in the gene can result in the variability in individual smoking response and addictive behavior by influencing the nicotine metabolism in the body .