Sandbox:DAMI

Table for HV

• The table below summarizes the classification of the herpesviridae family

	Classification	Clinical manifestations
Subfamily alphavirinae	Herpes simplex type 1	Perioral vesicular rash Rarely encephalitis Meningitis
	Herpes simplex type 2 varicella-zoster virus	Disseminated vesicular rash at acquisition (chicken pox) Localized vesicular rash with reactivation(zoster)
Subfamily betavirinae	Cytomegalovirus	Mononucleosis like illness in healthy adults Fever Pneumonia Hepatitis in immunocompromised adults
	Human herpes virus 6	Acute febrile illness sometimes with rash (roseola infantum)
	Human herpes virus 7	May cause febrile illness sometimes with rash ( roseola-like)
Subfamily gammavirinae	Epstein-Bar virus	mononucleosis, lymphoma, nasopahryngeal carcinoma and hodgkins disease.
	Human herpes virus 8	Kaposi's sarcoma in immunocompromised.

Question on Roseola

• A woman brings her 14 month old baby to the physician for the evaluation of a rash. He was in a good state of health until about 3 days ago when he developed a very high fever. The mother says the temperature was as high as 40C (104F) when she measured it with her thermometer at home. She gave him some tylenol and the fever subsided after which the rash developed. It started as a non itchy pink rash with rose spots on the head and is now generalized all over the body. Today the boy's temperature measured in the clinic is 37 C( 98F), pulse 88/min and respirations are 16/min. His immunizations are up to date and the boy is in no apparent distress. What is the most likely diagnosis in this patient?

A. Scarlet Fever B. Rubella(German measles C. Roseola (sixth disease) D. Rocky mountain spotted fever E. Measles F. Kawasaki disease G. Erythema infectiosum (fifth disease)