Progressive outer retinal necrosis
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
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Overview
Progressive outer retinal necrosis (PORN), also known as Varicella zoster virus retinitis (VZVR)[1], is an aggressive, necrotizing inflammation of the eye's retina caused by herpes varicella zoster virus. It is typically found in people with advanced AIDS, but has also been reported in those who are severely immunocompromised due to chemotherapy[2].
The majority of those with progressive outer retinal necrosis develop severe vision loss and blindness[3]. Systemic antiviral drugs may improve the long-term visual outcome in those with the disease[1].
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Progressive outer retinal necrosis from Other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications, and Prognosis
Natural History
Complications
Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
See also
- Cytomegalovirus retinitis
- List of eye diseases and disorders
- List of systemic diseases with ocular manifestations
References
- ↑ 1.0 1.1 Moorthy RS, Weinberg DV, Teich SA, Berger BB, Minturn JT, Kumar S, Rao NA, Fowell SM, Loose IA, Jampol LM. "Management of varicella zoster virus retinitis in AIDS." Br J Ophthalmol. 1997 Mar;81(3):189-94. PMID 9135381
- ↑ Copeland R, Phillpotts B. "Ocular Manifestations of HIV." eMedicine.com. January 20, 2005.
- ↑ Holland GN. "The progressive outer retinal necrosis syndrome." Int Ophthalmol. 1994;18(3):163-5. PMID 7852023.