Barrett's esophagus overview

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Barrett's esophagus refers to an abnormal change (metaplasia) in the cells of the lower end of the esophagus thought to be caused by damage from chronic acid exposure, or reflux esophagitis.[1] It is a condition in which any extent of metaplastic columnar epithelium replaces the normal stratified squamous epithelium in the distal esophagus.

Intestinal metaplasia is required for the diagnosis of Barrett's esophagus.[2]

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Barrett's esophagus overview from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Natural History

Complications

Prognosis

Diagnosis

Diagnostic Criteria

History and Symptoms

Physical Examination

Laboratory Findings

Imaging Findings

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Treatment

Medical Therapy

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References

  1. Stein H, Siewert J (1993). "Barrett's esophagus: pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management". Dysphagia. 8 (3): 276–88. PMID 8359051.
  2. Spechler SJ, Sharma P, Souza RF, Inadomi JM, Shaheen NJ (2011). "American Gastroenterological Association medical position statement on the management of Barrett's esophagus". Gastroenterology. 140 (3): 1084–91. PMID 21376940. Unknown parameter |month= ignored (help)

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