Sandbox:MDS

Revision as of 14:35, 8 December 2015 by Nawal Muazam (talk | contribs)
Jump to navigation Jump to search
Name Description
Refractory anemia
  • Less than 5% primitive blood cells (myeloblasts) in the bone marrow and pathological abnormalities primarily seen in red cell precursors.
Refractory anemia with ring sideroblasts (RARS)
  • Less than 5% myeloblasts in the bone marrow, but distinguished by the presence of 15% or greater red cell precursors in the marrow being abnormal iron-stuffed cells called ringed sideroblasts.
Refractory anemia with excess blasts (RAEB)
  • 5-20% myeloblasts in the marrow.
Refractory anemia with excess blasts in transformation (RAEB-T)
  • 21-30% myeloblasts in the marrow (>30% blasts is defined as acute myeloid leukemia).
Chronic myelomonocytic leukemia (CMML)
  • Less than 20% myeloblasts in the bone marrow and greater than 1*109/L monocytes in peripheral blood.



Old system New system
Refractory anemia
  • Refractory cytopenia with unilineage dysplasia
Refractory anemia with ringed sideroblasts
  • Refractory anemia with ring sideroblasts
:*Refractory cytopenia with multilineage dysplasia
Refractory anemia with excess blasts
  • Refractory anemias with excess blasts I and II


Refractory anemia with excess blasts in transformation I–IV
  • 5q - syndrome
Chronic myelomonocytic leukemia
  • Myelodysplastic-myeloproliferative overlap syndromes
  • Refractory cytopenia of childhood
  • Unclassifiable myelodysplastic syndrome