Sandbox:DDx HEENT

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  • Bimodal age distribution
  • Slowly enlarging mass in the parotid region
  • Bilateral and multicentric
  • Nonspecific appearance on CT
  • Hypoattenuating regions of central necrosis
  • Irregular enhancing solid component


  • Tubular, cribriform, and solid growth pattern
  • Uniform serous cells with pleomorphic nuclei and basophilic granular cytoplasms
  • Increased mitotic activity and foci of necrosis
  • Lymphoid stroma
  • c-KIT mutation
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