Meningioma medical therapy
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Meningioma Microchapters |
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Diagnosis |
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Meningioma medical therapy On the Web |
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American Roentgen Ray Society Images of Meningioma medical therapy |
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Risk calculators and risk factors for Meningioma medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]
Overview
Medical Therapy
Conservative management
- In asymptomatic meningiomas, the decision of surgical resection must be weighed against the possibility of conservative approach according to the patient's age, clinical presentation, and the anatomical location of the tumor.[1][2]
- Conservative management with close imaging follow-up is recommended among certain patients with small sized asymptomatic meningioma.[1][2]
- Meningioma among patients younger than 60 years of age are more likely to grow in size on repeated imaging studies; thus conservative approach is not recommended among such patients.[1][2]
- Observation is not recommended among meningioma patients who are already symptomatic.[1][2]
Radiation therapy
Radiation therapy including Gamma Knife or proton beam treatment, may be pursued in cases of inoperable or unresectable tumors, or if tumor shows malignant transformation. Focused radiation may also be helpful for small tumors at the base of the skull.
Chemotherapy
Conventional chemotherapy is likely not effective. Antiprogestin agents have been used, but with variable results. Recent evidence that hydroxyurea has the capacity to shrink unresectable or recurrent meningiomas is being further evaluated.
References
- ↑ 1.0 1.1 1.2 1.3 Herscovici Z, Rappaport Z, Sulkes J, Danaila L, Rubin G (2004). "Natural history of conservatively treated meningiomas". Neurology. 63 (6): 1133–4. PMID 15452322.
- ↑ 2.0 2.1 2.2 2.3 Meningioma. Wikipedia(2015) https://en.wikipedia.org/wiki/Meningioma Accessed on September, 25th 2015