Major or mild neurocognitive disorder due to Parkinson's disease

Parkinson's disease Microchapters
Home
Patient Information
Overview
Historical Perspective
Pathophysiology
Causes
Differentiating Parkinson's disease from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Neurocognitive Disorder Due to Parkinson's Disease
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X-ray
Echocardiography and Ultrasound
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Major or mild neurocognitive disorder due to Parkinson's disease On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Major or mild neurocognitive disorder due to Parkinson's disease All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Major or mild neurocognitive disorder due to Parkinson's disease
CDC on Major or mild neurocognitive disorder due to Parkinson's disease
Major or mild neurocognitive disorder due to Parkinson's disease in the news
Blogs on Major or mild neurocognitive disorder due to Parkinson's disease
Directions to Hospitals Treating Parkinson's disease
Risk calculators and risk factors for Major or mild neurocognitive disorder due to Parkinson's disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Major or Mild Neurocognitive Disorder Due to Parkinson's Disease

DSM-V Diagnostic Criteria for Major or Mild Neurocognitive Disorder Due to Parkinson's Disease

“

A.The criteria are met for major or mild neurocognitive disorder. AND B.The disturbance occurs in the setting of established Parkinson’s disease. AND C.There is insidious onset and gradual progression of impairment. AND D.The neurocognitive disorder is not attributable to another medical condition and is not better explained by another mental disorder. Major or mild neurocognitive disorder probably due to Parkinson’s disease should be diagnosed if 1 and 2 are both met. Major or mild neurocognitive disorder possibly due to Parkinson’s disease should be diagnosed if 1 or 2 is met: 1.There is no evidence of mixed etiology (i.e., absence of other neurodegenerative or cerebrovascular disease or another neurological, mental, or systemic disease or condition likely contributing to cognitive decline). 2.The Parkinson’s disease clearly precedes the onset of the neurocognitive disorder.

”

Epidemiology and Demographics

Prevalence

The prevalence of major or mild neurocognitive disorder due to parkinson's disease is:

75,000 per 100,000 (75%) major neurocognitive disorder.

27,000 per 100,000 (27%) mild neurocognitive disorder.

Risk Factors

• Herbicides
• Increasing duration of disease

• Older age at disease onset

• Pesticides

Differential Diagnosis

• Major or mild neurocognitive disorder due to Alzheimer’s disease
• Major or mild neurocognitive disorder with Lewy bodies
• Major or mild vascular neurocognitive disorder
• Neurocognitive disorder due to another medical condition (e.g., neurodegenerative disorders)

• Corticobasal degeneration
• Hydrocephalus
• Multiple system atrophy
• Progressive supranuclear palsy
• Tumors

• Neuroleptic-induced parkinsonism
• Other medical conditions

• B12 deficiency
• Delirium
• Hypothyroidism
• Impaired cognition
• Side effects of dopamine-blocking drugs
• Sedation