RAB3A

RAB3A, member RAS oncogene family
File:PBB Protein RAB3A image.jpg PDB rendering based on 1zbd.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1zbd​, 3rab​
Identifiers
Symbols	RAB3A ;
External IDs	Template:OMIM5 Template:MGI HomoloGene: 20629
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RAB3A 204974 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

RAB3A, member RAS oncogene family, also known as RAB3A, is a human gene.

Further reading

• Khosravi-Far R, Lutz RJ, Cox AD; et al. (1991). "Isoprenoid modification of rab proteins terminating in CC or CXC motifs". Proc. Natl. Acad. Sci. U.S.A. 88 (14): 6264–8. PMID 1648736.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zahraoui A, Touchot N, Chardin P, Tavitian A (1989). "The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion". J. Biol. Chem. 264 (21): 12394–401. PMID 2501306.CS1 maint: Multiple names: authors list (link)
• Rousseau-Merck MF, Zahraoui A, Bernheim A; et al. (1990). "Chromosome mapping of the human ras-related rab3A gene to 19p13.2". Genomics. 5 (4): 694–8. PMID 2687157.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Brondyk WH, McKiernan CJ, Fortner KA; et al. (1995). "Interaction cloning of Rabin3, a novel protein that associates with the Ras-like GTPase Rab3A". Mol. Cell. Biol. 15 (3): 1137–43. PMID 7532276.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Farnsworth CC, Seabra MC, Ericsson LH; et al. (1995). "Rab geranylgeranyl transferase catalyzes the geranylgeranylation of adjacent cysteines in the small GTPases Rab1A, Rab3A, and Rab5A". Proc. Natl. Acad. Sci. U.S.A. 91 (25): 11963–7. PMID 7991565.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• McKiernan CJ, Brondyk WH, Macara IG (1993). "The Rab3A GTPase interacts with multiple factors through the same effector domain. Mutational analysis of cross-linking of Rab3A to a putative target protein". J. Biol. Chem. 268 (32): 24449–52. PMID 8226995.CS1 maint: Multiple names: authors list (link)
• Trask B, Fertitta A, Christensen M; et al. (1993). "Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers". Genomics. 15 (1): 133–45. PMID 8432525.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Johannes L, Perez F, Laran-Chich MP; et al. (1996). "Characterization of the interaction of the monomeric GTP-binding protein Rab3a with geranylgeranyl transferase II". Eur. J. Biochem. 239 (2): 362–8. PMID 8706741.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Burton JL, Slepnev V, De Camilli PV (1997). "An evolutionarily conserved domain in a subfamily of Rabs is crucial for the interaction with the guanyl nucleotide exchange factor Mss4". J. Biol. Chem. 272 (6): 3663–8. PMID 9013620.CS1 maint: Multiple names: authors list (link)
• Geppert M, Goda Y, Stevens CF, Südhof TC (1997). "The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion". Nature. 387 (6635): 810–4. doi:10.1038/42954. PMID 9194562.CS1 maint: Multiple names: authors list (link)
• Martincic I, Peralta ME, Ngsee JK (1997). "Isolation and characterization of a dual prenylated Rab and VAMP2 receptor". J. Biol. Chem. 272 (43): 26991–8. PMID 9341137.CS1 maint: Multiple names: authors list (link)
• Ostermeier C, Brunger AT (1999). "Structural basis of Rab effector specificity: crystal structure of the small G protein Rab3A complexed with the effector domain of rabphilin-3A". Cell. 96 (3): 363–74. PMID 10025402.
• Jung YJ, Lee TH, Lee JY; et al. (1999). "Phosphatidic acid is important to the translocation of Rab3A from the cytosol to phospholipid membranes". Neuroreport. 10 (13): 2859–63. PMID 10511453.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Sullivan M, Olsen AS, Houslay MD (2000). "Genomic organisation of the human cyclic AMP-specific phosphodiesterase PDE4C gene and its chromosomal localisation to 19p13.1, between RAB3A and JUND". Cell. Signal. 11 (10): 735–42. PMID 10574328.CS1 maint: Multiple names: authors list (link)
• Clabecq A, Henry JP, Darchen F (2000). "Biochemical characterization of Rab3-GTPase-activating protein reveals a mechanism similar to that of Ras-GAP". J. Biol. Chem. 275 (41): 31786–91. doi:10.1074/jbc.M003705200. PMID 10859313.CS1 maint: Multiple names: authors list (link)
• Haynes LP, Evans GJ, Morgan A, Burgoyne RD (2001). "A direct inhibitory role for the Rab3-specific effector, Noc2, in Ca2+-regulated exocytosis in neuroendocrine cells". J. Biol. Chem. 276 (13): 9726–32. doi:10.1074/jbc.M006959200. PMID 11134008.CS1 maint: Multiple names: authors list (link)
• Zhang Y, Luan Z, Liu A, Hu G (2001). "The scaffolding protein CASK mediates the interaction between rabphilin3a and beta-neurexins". FEBS Lett. 497 (2–3): 99–102. PMID 11377421.CS1 maint: Multiple names: authors list (link)
• Luo HR, Saiardi A, Nagata E; et al. (2001). "GRAB: a physiologic guanine nucleotide exchange factor for Rab3A, which interacts with inositol hexakisphosphate kinase". Neuron. 31 (3): 439–51. PMID 11516400.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Piiper A, Leser J, Lutz MP; et al. (2001). "Subcellular distribution and function of Rab3A-D in pancreatic acinar AR42J cells". Biochem. Biophys. Res. Commun. 287 (3): 746–51. doi:10.1006/bbrc.2001.5651. PMID 11563859.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kuroda TS, Fukuda M, Ariga H, Mikoshiba K (2002). "The Slp homology domain of synaptotagmin-like proteins 1-4 and Slac2 functions as a novel Rab27A binding domain". J. Biol. Chem. 277 (11): 9212–8. doi:10.1074/jbc.M112414200. PMID 11773082.CS1 maint: Multiple names: authors list (link)