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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: M. Khurram Afzal, MD [2]

Overview

Alcoholic Liver Disease

  • Alcohol
    • Jaundice
      • Gamma GT

First Strike

Overview

There are no established risk factors for [disease name].

OR

The most potent risk factor in the development of [disease name] is [risk factor 1]. Other risk factors include [risk factor 2], [risk factor 3], and [risk factor 4].

OR

Common risk factors in the development of [disease name] include [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].

OR

Common risk factors in the development of [disease name] may be occupational, environmental, genetic, and viral.

Risk Factors

The most potent risk factor in the development of alcoholic liver disease is the quantity and frequency of alcohol consumption. Other risk factors include gender, age, and genetic factors.[1][2]

Common Risk Factors

  • Common risk factors in the development of alcoholic liver disease include:
    • Female gender
    • Ethnicity
    • Obesity
    • Genetic factors

Less Common Risk Factors

  • Less common risk factors in the development of alcoholic liver disease include:
    • Age
    • Co-existing chronic viral hepatitis
    • Iron overload
    • Smoking

References

  1. Bertola A, Park O, Gao B (2013). "Chronic plus binge ethanol feeding synergistically induces neutrophil infiltration and liver injury in mice: a critical role for E-selectin". Hepatology. 58 (5): 1814–23. doi:10.1002/hep.26419. PMC 3726575. PMID 23532958.
  2. Anstee QM, Daly AK, Day CP (2011). "Genetics of alcoholic and nonalcoholic fatty liver disease". Semin Liver Dis. 31 (2): 128–46. doi:10.1055/s-0031-1276643. PMID 21538280.