Hemophilia A cost-effectiveness of therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Fahd Yunus, M.D. [2]
Overview
Though long-term prophylaxis has been shown to be beneficial in decreasing incidence of bleeding events, the major barrier to its implementation is high cost.
Cost-effectiveness of therapy
Long-term prophylaxis, particularly for patients with severe hemophilia, has been shown to be cost-effective as it decreases the otherwise high cost of managing recurrent joint bleeds and improves quality of life overall. [1] Further research is required to address the issue of cost-effectiveness for therapy in hemophilia A. In particular, further research would be helpful to determine the optimal dosing schedule for prophylaxis, and the optimal target ranges of clotting factor levels. These studies are especially needed in countries with limited resources, where access to prophylaxis is limited.
References
- ↑ Prophylaxis: Barriers and challenges – World Federation of Hemophilia. Available at http://www.wfh.org/en/abd/prophylaxis/prophylaxis-barriers-and-challenges. Accessed on Sept 20, 2016