Zollinger-Ellison syndrome natural history, complications and prognosis

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Zollinger-Ellison syndrome Microchapters

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Overview

If left untreated, patients with Zollinger-Ellison syndrome may progress to develop abdominal pain, diarrhea, and heartburn[1]. Common complications of Zollinger-Ellison syndrome include upper gastrointestinal bleeding, anemia, and [gastric ulcer perforation]. Prognosis is generally good, and the 5 and 10-year survival rate of patients with Zollinger-Ellison syndrome is approximately 94% and 75%, respectively.[2]

References

  1. Roy PK, Venzon DJ, Shojamanesh H, Abou-Saif A, Peghini P, Doppman JL; et al. (2000). "Zollinger-Ellison syndrome. Clinical presentation in 261 patients". Medicine (Baltimore). 79 (6): 379–411. PMID 11144036.
  2. Melvin WS, Johnson JA, Sparks J, Innes JT, Ellison EC (1993). "Long-term prognosis of Zollinger-Ellison syndrome in multiple endocrine neoplasia". Surgery. 114 (6): 1183–8. PMID 7903006.

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