WBR0316
| Author | [[PageAuthor::Ogheneochuko Ajari, MB.BS, MS [1] (Reviewed by Alison Leibowitz)]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Embryology |
| Sub Category | SubCategory::Reproductive |
| Prompt | Prompt::In normal female development, the genital tubercle gives rise to the glans clitoris. In typical male development, the faulty positioning of the genital tubercle would give rise to which of the following? |
| Answer A | AnswerA::Hydrocele of the testis |
| Answer A Explanation | [[AnswerAExp::Hydrocele of the testis forms as a result of the development of a fluid-filled sac within the scrotum, which results from an incomplete obliteration of the processus vaginalis.]] |
| Answer B | AnswerB::Cryptoorchidism |
| Answer B Explanation | [[AnswerBExp::The cryptoorchidism results from failure of the fetal testis to descend into the scrotum.]] |
| Answer C | AnswerC::Bifid scrotum |
| Answer C Explanation | [[AnswerCExp::Bifid scrotum develops as a result of malunion of the labioscrotal folds, which forms the labia majora in females.]] |
| Answer D | AnswerD::Hypospadias |
| Answer D Explanation | [[AnswerDExp::Hypospadias results from an abnormal opening of the penile urethra on the inferior (ventral) side of the penis, due to the failure of the urethral folds to close.]] |
| Answer E | AnswerE::Epispadias |
| Answer E Explanation | AnswerEExp::See Explanation |
| Right Answer | RightAnswer::E |
| Explanation | [[Explanation::In normal fetal development, the genital tubercle gives rise to the glans clitoris and vestibular bulbs in the female and the glans penis and corpus carvernosum in males. The abnormal opening of the penile urethra on superior (dorsal) side of the penis due to faulty positioning of the genital tubercle give rise to Epispadias (Choice E). Extrophy of the bladder is associated with Epispadias. Educational Objective: Epispadias arise due to the faulty positioning of the genital tubercle during development of the glans penis. |
| Approved | Approved::Yes |
| Keyword | WBRKeyword::Fetal development, WBRKeyword::genital tubercle, WBRKeyword::glans clitoris, WBRKeyword::glans penis |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |