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Overview

Venous thromboembolism (VTE) consists of deep vein thrombosis (DVT), pulmonary embolism (PE), or both. The risk factors for VTE are a constellation of predisposing conditions which stem from the three principles of Virchow's triad: stasis of the blood flow, damage to the vascular endothelial cells, and hypercoagulability. The risk factors for VTE can be categorized as temporary, modifiable and non-modifiable. Venous thrombosis also shares risk factors with cardiac thrombosis, such as obesity, hypertension and smoking.

Risk Factors

Shown below is a list of predisposing factors to VTE.

Strong risk factors Moderate risk factors Weak risk factors
Bone fracture (hip or leg)

Hip replacement surgery
❑ Knee replacement surgery
Major general surgery
Significant trauma
Spinal cord injury

❑ Athroscopic knee surgery

Central venous lines
Chemotherapy
Chronic heart failure
Respiratory failure
Hormone replacement therapy
Cancer
Oral contraceptive pills
Stroke
Pregnancy
Postpartum
❑ Prior history of VTE
Thrombophilia

❑ Bed rest for more than 3 days

❑ Prolonged car or air travel
❑ Advanced age
Laparoscopic surgery
❑ Prepartum
Obesity
Varicose veins