Cystitis pathophysiology
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Pathophysiology
Cystitis occurs when the normally sterile lower urinary tract (urethra and bladder) is infected by bacteria and becomes irritated and inflamed. It is very common [citation needed].
The condition frequently affects sexually active women ages 20 to 50 but may also occur in those who are not sexually active or in young girls. Sexual intercourse may increase the risk of cystitis because bacteria can be introduced into the bladder through the urethra during sexual activity. Once bacteria enter the bladder, they are normally removed through urination. When bacteria multiply faster than they are removed by urination, infection results.Older adults are also at high risk for developing cystitis, with the incidence in the elderly being much higher than in younger people.
Cystitis is rare in males. Females are more prone to the development of cystitis because of their relatively shorter urethra and bacteria do not have to travel as far to enter the bladder and because of the relatively short distance between the opening of the urethra and the anus.