Meckel's diverticulum epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sudarshana Datta, MD [2]
Overview
Meckel's diverticulum is present in approximately 2% of the population, with males more frequently experiencing symptoms.
Epidemiology and Demographics
Incidence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
Prevalence
- The incidence/prevalence of [disease name] is approximately [number range] per 100,000 individuals worldwide.
- In [year], the incidence/prevalence of [disease name] was estimated to be [number range] cases per 100,000 individuals worldwide.
- The prevalence of [disease/malignancy] is estimated to be [number] cases annually.
Case-fatality rate/Mortality rate
- In [year], the incidence of [disease name] is approximately [number range] per 100,000 individuals with a case-fatality rate/mortality rate of [number range]%.
- The case-fatality rate/mortality rate of [disease name] is approximately [number range].
Age
- Patients of all age groups may develop [disease name].
- The incidence of [disease name] increases with age; the median age at diagnosis is [#] years.
- [Disease name] commonly affects individuals younger than/older than [number of years] years of age.
- [Chronic disease name] is usually first diagnosed among [age group].
- [Acute disease name] commonly affects [age group].
Race
- There is no racial predilection to [disease name].
- [Disease name] usually affects individuals of the [race 1] race. [Race 2] individuals are less likely to develop [disease name].
Gender
- [Disease name] affects men and women equally.
- [Gender 1] are more commonly affected by [disease name] than [gender 2]. The [gender 1] to [gender 2] ratio is approximately [number > 1] to 1.
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
EPID Most common congenital anomaly of the gastrointestinal tract No genetic component Rule of 2s: occurs in approximately 2 percent of the population: range from 0.2-4% male-to-female ratio of 2:1 is located within two feet from the ileocecal valve two inches in length <2yrs 2 types of mucosa mostly: gastric> pancreatic Complications are only seen in about 5% 2 feet (proximal to the ileocecal valve) 2 inches (in length) 2 types of common ectopic tissue (gastric and pancreatic) 2 years is the most common age at clinical presentation
Prevalence: Prevalence of MD- 2 percent of the general population Increased prevalence in children with: Umbilical malformations GI tract defects Neurological and cardiovascular defects Slightly more than half (60%) were symptomatic and the remainder were incidental in children GENDER: 2:1 M:F males are as much as 3-4 times more prone to complications than females Race The ethnic distribution of symptomatic Meckel diverticulum was 63.4% white, 4.7% African-American, 16.4% Hispanic, 3.9% Asian, and 11.6% other.
The classic presentation in children is considered to be painless rectal bleeding in a toddler younger than 2 years., the largest group (slightly more than 30%) were younger than one year.
Younger children have been reported to usually present with hematochezia and adults with obstruction, common presentations: (30%) for obstruction bleeding (27%) (19%) intussusception
Neonatal period most common manifestations bowel obstruction (58.3%) pneumoperitoneum (33.3%).
In adults, obstruction inflammation lower GI bleeding