Microsporidiosis history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2] Ogheneochuko Ajari, MB.BS, MS [3]

Overview

Symptoms of intestinal microsporidiosis include chronic diarrhea, abdominal pain, and weight loss.[1]

History and Symptoms

History

History about the presence and risk factors of an immune compromised state should be assessed. The duration and severity of diarrhea should be investigated to stratify the risk for the presence of complications.

Symptoms

Microsporidiosis can affect many systems.[1][2]

Intestinal microsporidiosis

Intestinal microsporidiosis is the most common form of the disease.

Intestinal microsporidiosis may be asymptomatic or causes transient diarrhea. In rare cases, it might cause chronic diarrhea.

Disseminated disease

Eye involvement

Ocular involvement can cause keratitis which presents with;

Musculoskeletal involvement

Dermatologic Microsporidiosis

  • Nodular cutaneous lesions are seen in patients with HIV infection.

Central nervous system involvement

Microsporidiosis may present with symptoms of space occupying lesions such as:

References

  1. 1.0 1.1 Wanke CA, DeGirolami P, Federman M (1996). "Enterocytozoon bieneusi infection and diarrheal disease in patients who were not infected with human immunodeficiency virus: case report and review". Clin. Infect. Dis. 23 (4): 816–8. PMID 8909851.
  2. Weber R, Bryan RT, Schwartz DA, Owen RL (1994). "Human microsporidial infections". Clin. Microbiol. Rev. 7 (4): 426–61. PMC 358336. PMID 7834600.