Profenamine

Profenamine

Clinical data
AHFS/Drugs.com	International Drug Names
ATC code	N04AA05 (WHO)
Pharmacokinetic data
Protein binding	93%
Elimination half-life	1 to 2 hours
Identifiers
IUPAC name N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine
CAS Number	1094-08-2 Y
PubChem CID	3290
DrugBank	DB00392 Y
ChemSpider	3174 Y
UNII	O00T1I1VRN
ChEBI	CHEBI:313639 Y
ChEMBL	ChEMBL1206 Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C19H24N2S
Molar mass	312.473 g/mol
3D model (JSmol)	Interactive image
SMILES S2c1ccccc1N(c3c2cccc3)CC(N(CC)CC)C
InChI InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3 Y Key:CDOZDBSBBXSXLB-UHFFFAOYSA-N Y
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Profenamine (INN, trade names Parsidol, Parsidan, Parkin), also known as ethopropazine (BAN), is a phenothiazine derivative used as an antiparkinsonian agent that has anticholinergic, antihistamine, and antiadrenergic actions. It is also used in the alleviation of the extrapyramidal syndrome induced by drugs such as other phenothiazine compounds, but, like other compounds with antimuscarinic properties, is of no value against tardive dyskinesia.