Ticlopidine overdosage: Difference between revisions

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#REDIRECT [[Ticlopidine#Overdosage]]
{{Ticlopidine}}
{{CMG}}; {{AE}} {{AZ}}


==Overdosage==
[[Category: Cardiovascular Drugs]]
 
[[Category: Drug]]
One case of deliberate overdosage with ticlopidine has been reported by a foreign postmarketing surveillance program. A 38-year-old male took a single 6000-mg dose of ticlopidine (equivalent to 24 standard 250-mg tablets). The only abnormalities reported were increased [[bleeding time]] and increased SGPT. No special therapy was instituted and the patient recovered without sequelae.
[[Category:Antiplatelet drugs]]
 
Single oral doses of ticlopidine at 1600 mg/kg and 500 mg/kg were lethal to rats and mice, respectively.
 
Symptoms of acute toxicity were GI [[hemorrhage]], [[convulsions]], [[hypothermia]], [[dyspnea]], loss of equilibrium and abnormal gait.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = TICLOPIDINE HYDROCHLORIDE TABLET, FILM COATED [APOTEX CORP.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=707127cb-cdcd-81b0-274d-3c11fefa6824 | publisher =  | date =  | accessdate = }}</ref>
==References==
{{Reflist}}
 
{{FDA}}
 
[[Category:Drugs]]

Revision as of 19:50, 21 July 2014