Betaxolol nonclinical toxicology: Difference between revisions

Latest revision as of 16:21, 21 July 2014

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+#REDIRECT [[Betaxolol#Nonclinical Toxicology]]
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-==Nonclinical Toxicology==
-===Carcinogenesis, Mutagenesis, Impairment of Fertility===
-Lifetime studies with betaxolol HCl have been completed in mice at oral doses of 6, 20 or 60 mg/kg/day and in rats at 3, 12, or 48 mg/kg/day; betaxolol HCl demonstrated no carcinogenic effect. Higher dose levels were not tested.
-In a variety of in vitro and in vivo bacterial and mammalian cell assays, betaxolol HCl was nonmutagenic.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = BETOPTIC (BETAXOLOL HYDROCHLORIDE) SOLUTION/ DROPS [ALCON] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=31b9b263-11fd-4495-83dd-ababf0d70e9e | publisher =  | date =  | accessdate = 3 February 2014 }}</ref>
-==References==
-{{Reflist|2}}
 [[Category:Beta blockers]]
 [[Category:Cardiovascular Drugs]]
 [[Category:Drugs]]
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