Vertebrobasilar insufficiency natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
| Line 11: | Line 11: | ||
===Prognosis=== | ===Prognosis=== | ||
The prognosis of VBI vary depending on the severity of symptoms the patients present | The prognosis of VBI vary depending on the severity of symptoms the patients present, such as: | ||
For patients who experience vertebrobasilar [[transient ischemic attack]] | *Severe [[stroke]] or [[TIA]]? | ||
<ref name="pmid7368245">Jones HR, Millikan CH, Sandok BA (1980) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7368245 Temporal profile (clinical course) of acute vertebrobasilar system cerebral infarction.] ''Stroke'' 11 (2):173-7. PMID: [http://pubmed.gov/7368245 7368245]</ref><ref name="pmid13773892">MCDOWELL FH, POTES J, GROCH S (1961) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=13773892 The natural history of internal carotid and vertebral-basilar artery occlusion.] ''Neurology'' 11(4)Pt2 ():153-7. PMID: [http://pubmed.gov/13773892 13773892]</ref><ref name="pmid7210071">Patrick BK, Ramirez-Lassepas M, Synder BD (1980) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7210071 Temporal profile of vertebrobasilar territory infarction. Prognostic implications.] ''Stroke'' 11 (6):643-8. PMID: [http://pubmed.gov/7210071 7210071]</ref> | *The type of [[stroke]]?Ischemic and hemorrhagic? | ||
*The size and location of infarction or hemorrhage? | |||
*If the patient get an early diagnosis and treatment or not? | |||
For patients who experience vertebrobasilar [[transient ischemic attack]] portends a 30%to 35% risk for stroke during a 5-year period.<ref name="pmid609290">Cartlidge NE, Whisnant JP, Elveback LR (1977) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=609290 Carotid and vertebral-basilar transient cerebral ischemic attacks. A community study, Rochester, Minnesota.] ''Mayo Clin Proc'' 52 (2):117-20. PMID: [http://pubmed.gov/609290 609290]</ref><ref name="pmid6538654">Heyman A, Wilkinson WE, Hurwitz BJ, Haynes CS, Utley CM, Rosati RA et al. (1984) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=6538654 Risk of ischemic heart disease in patients with TIA.] ''Neurology'' 34 (5):626-30. PMID: [http://pubmed.gov/6538654 6538654]</ref><ref name="pmid655661">Whisnant JP, Cartlidge NE, Elveback LR (1978) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=655661 Carotid and vertebral-basilar transient ischemic attacks: effect of anticoagulants, hypertension, and cardiac disorders on survival and stroke occurrence--a population study.] ''Ann Neurol'' 3 (2):107-15. [http://dx.doi.org/10.1002/ana.410030204 DOI:10.1002/ana.410030204] PMID: [http://pubmed.gov/655661 655661]</ref> Medical refractory disease of the vertebrobasilar system carries a 5% to 11% risk of [[stroke]] or death at 1 year.<ref name="pmid12847074">Flossmann E, Rothwell PM (2003)[http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12847074 Prognosis of vertebrobasilar transient ischaemic attack and minor stroke.]''Brain'' 126 (Pt 9):1940-54. [http://dx.doi.org/10.1093/brain/awg197 DOI:10.1093/brain/awg197] PMID: [http://pubmed.gov/12847074 12847074]</ref> Mortality associated with a [[stroke]] is high, ranging from 20% to 30%.<ref name="pmid12847074">Flossmann E, Rothwell PM (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12847074 Prognosis of vertebrobasilar transient ischaemic attack and minor stroke.] ''Brain'' 126 (Pt 9):1940-54.[http://dx.doi.org/10.1093/brain/awg197 DOI:10.1093/brain/awg197] PMID: [http://pubmed.gov/12847074 12847074]</ref> | |||
<ref name="pmid7368245">Jones HR, Millikan CH, Sandok BA (1980) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7368245 Temporal profile (clinical course) of acute vertebrobasilar system cerebral infarction.] ''Stroke'' 11 (2):173-7. PMID: [http://pubmed.gov/7368245 7368245]</ref><ref name="pmid13773892">MCDOWELL FH, POTES J, GROCH S (1961) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=13773892 The natural history of internal carotid and vertebral-basilar artery occlusion.] ''Neurology'' 11(4)Pt2 ():153-7. PMID: [http://pubmed.gov/13773892 13773892]</ref><ref name="pmid7210071">Patrick BK, Ramirez-Lassepas M, Synder BD (1980) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=7210071 Temporal profile of vertebrobasilar territory infarction. Prognostic implications.] ''Stroke'' 11 (6):643-8. PMID: [http://pubmed.gov/7210071 7210071]</ref> Patients presenting with VB events are more likely to have a recurrent [[TIA]] than patients with carotid events, and patients with VBI caused minor [[stroke]] and [[TIA]] have a higher risk of [[stroke]] than patients with carotid events in the acute phase, but that this is reversed in the subacute and chronic.<ref name="pmid12847074">Flossmann E, Rothwell PM (2003) [http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&retmode=ref&cmd=prlinks&id=12847074 Prognosis of vertebrobasilar transient ischaemic attack and minor stroke.] ''Brain'' 126 (Pt 9):1940-54. [http://dx.doi.org/10.1093/brain/awg197 DOI:10.1093/brain/awg197] PMID: [http://pubmed.gov/12847074 12847074]</ref> | |||
===Complications=== | ===Complications=== | ||
Revision as of 19:35, 9 December 2013
| Vertebrobasilar insufficiency
|
|
Differentiating Vertebrobasilar insufficiency from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Case Studies |
|
Vertebrobasilar insufficiency natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Vertebrobasilar insufficiency natural history, complications and prognosis |
|
FDA onVertebrobasilar insufficiency natural history, complications and prognosis |
|
CDC on Vertebrobasilar insufficiency natural history, complications and prognosis |
|
Vertebrobasilar insufficiency natural history, complications and prognosis in the news |
|
on Vertebrobasilar insufficiency natural history, complications and prognosis |
|
Directions to Hospitals Treating Vertebrobasilar insufficiency |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Natural History, Complications and Prognosis
Natural History
Some VBI is caused by the embolus from subclavian artery or atherosclerotic lesions and dissection, etc. Once the blocked vertebral artery doesn't get enough compensation from the contralateral, obviously multiple and multifocal infarcts in the brain stem, cerebellum symptoms will be observed immediately,and quickly develop to a severe outcome. Some patients present nonspecific symptoms, such as nausea, tinnitus, hearing impairment, and vertigo, which can precede the onset of the monophasic, progressive deficits by days, but typically by several weeks.
Prognosis
The prognosis of VBI vary depending on the severity of symptoms the patients present, such as:
- Severe stroke or TIA?
- The type of stroke?Ischemic and hemorrhagic?
- The size and location of infarction or hemorrhage?
- If the patient get an early diagnosis and treatment or not?
For patients who experience vertebrobasilar transient ischemic attack portends a 30%to 35% risk for stroke during a 5-year period.[1][2][3] Medical refractory disease of the vertebrobasilar system carries a 5% to 11% risk of stroke or death at 1 year.[4] Mortality associated with a stroke is high, ranging from 20% to 30%.[4] [5][6][7] Patients presenting with VB events are more likely to have a recurrent TIA than patients with carotid events, and patients with VBI caused minor stroke and TIA have a higher risk of stroke than patients with carotid events in the acute phase, but that this is reversed in the subacute and chronic.[4]
Complications
Complications of vertebrobasilar circulatory disorders are stroke and its complications. The complications of stroke include:
- Respiratory (breathing) failure (which may require use of a machine to help the patient breathe)
- Lung problems (especially lung infections)
- Heart attack
- Dehydration and swallowing problems (sometimes leading to the placement of tubes in the stomach for artificial feeding)
- Problems with movement or sensation, including paralysis and numbness
- Formation of clots in the legs
Complications caused by medications or surgery may also occur.
References
- ↑ Cartlidge NE, Whisnant JP, Elveback LR (1977) Carotid and vertebral-basilar transient cerebral ischemic attacks. A community study, Rochester, Minnesota. Mayo Clin Proc 52 (2):117-20. PMID: 609290
- ↑ Heyman A, Wilkinson WE, Hurwitz BJ, Haynes CS, Utley CM, Rosati RA et al. (1984) Risk of ischemic heart disease in patients with TIA. Neurology 34 (5):626-30. PMID: 6538654
- ↑ Whisnant JP, Cartlidge NE, Elveback LR (1978) Carotid and vertebral-basilar transient ischemic attacks: effect of anticoagulants, hypertension, and cardiac disorders on survival and stroke occurrence--a population study. Ann Neurol 3 (2):107-15. DOI:10.1002/ana.410030204 PMID: 655661
- ↑ 4.0 4.1 4.2 Flossmann E, Rothwell PM (2003)Prognosis of vertebrobasilar transient ischaemic attack and minor stroke.Brain 126 (Pt 9):1940-54. DOI:10.1093/brain/awg197 PMID: 12847074
- ↑ Jones HR, Millikan CH, Sandok BA (1980) Temporal profile (clinical course) of acute vertebrobasilar system cerebral infarction. Stroke 11 (2):173-7. PMID: 7368245
- ↑ MCDOWELL FH, POTES J, GROCH S (1961) The natural history of internal carotid and vertebral-basilar artery occlusion. Neurology 11(4)Pt2 ():153-7. PMID: 13773892
- ↑ Patrick BK, Ramirez-Lassepas M, Synder BD (1980) Temporal profile of vertebrobasilar territory infarction. Prognostic implications. Stroke 11 (6):643-8. PMID: 7210071