Fungal meningitis laboratory findings: Difference between revisions
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*''[[Cryptococcus neoformans]]'' | *''[[Cryptococcus neoformans]]'' | ||
**India ink or fungal wet mount of CSF (budding yeast) | **India ink or fungal wet mount of CSF (budding yeast) | ||
**Mucicarmine stain provides specific staining of the polysaccharide cell wall | |||
**Blood and urine cultures | **Blood and urine cultures | ||
**Antigen detection in CSF | **Antigen detection in CSF | ||
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CSF culture<ref>Koroshetz WJ. Chapter 382. Chronic and Recurrent Meningitis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012.</ref> | CSF culture<ref>Koroshetz WJ. Chapter 382. Chronic and Recurrent Meningitis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012.</ref> | ||
===Fungal | ===Fungal Stains=== | ||
<gallery> | |||
Blastomycosis.JPG|Blastomyces:Broad based budding | |||
Cryptococcus_neoformans_India_ink_staining.jpg|Cryptococcus: clear halo visualized by the india ink stain | |||
Histoplasma_capsulatum.jpg|Histoplama capsulatum | |||
</gallery> | |||
==References== | ==References== | ||
Revision as of 18:06, 22 October 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Assistant Editor(s)-in-Chief: Rim Halaby
Overview
Laboratory Findings
The General characteristic CSF Findings in Fungal Meningitis:
- Mononuclear or lymphocytic pleocytosis
- An elevated protein concentration
- A decreased glucose concentration
Other CSF Findings and Serology Tests Specific to Each Particular Fungi
- Aspergillus sp.
- CSF culture
- Blastomyces dermatitidis
- Fungal stain and culture of CSF
- Biopsy and culture of skin, lung lesions
- Antibody detection in serum
- Cryptococcus neoformans
- India ink or fungal wet mount of CSF (budding yeast)
- Mucicarmine stain provides specific staining of the polysaccharide cell wall
- Blood and urine cultures
- Antigen detection in CSF
- Coccidioides immitis
- Antibody detection in CSF and serum
- Candida sp.
- Fungal stain and culture of CSF
- Histoplasma capsulatum
- Fungal stain and culture of large volumes of CSF
- Antigen detection in CSF, serum, and urine
- Antibody detection in serum and CSF
- Sporothrix schenckii
- Antibody detection in CSF and serum
CSF culture[1]
Fungal Stains
-
Blastomyces:Broad based budding
-
Cryptococcus: clear halo visualized by the india ink stain
-
Histoplama capsulatum
References
- ↑ Koroshetz WJ. Chapter 382. Chronic and Recurrent Meningitis. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson JL, Loscalzo J, eds. Harrison's Principles of Internal Medicine. 18th ed. New York: McGraw-Hill; 2012.