Primary central nervous system lymphoma pathophysiology: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
(Created page with "{{CMG}} {{Primary central nervous system lymphoma}} ==Overview== '''Primary CNS lymphoma''' is a primary intracranial tumor usually present in those with sever...")
 
No edit summary
Line 1: Line 1:
{{CMG}}
__NOTOC__
{{Primary central nervous system lymphoma}}
{{Primary central nervous system lymphoma}}
==Overview==
 
'''Primary CNS lymphoma''' is a [[brain tumor|primary intracranial tumor]] usually present in those with severe immunosuppression --- commonly in those with [[AIDS]] --- and represents around 20% of all cases of lymphomas in HIV infection (other types being [[Burkitt's lymphoma]] and immunoblastic lymphoma). Primary CNS lymphoma (PCNSL) is highly associated with [[Epstein-Barr virus]] infection (> 90%) in immunodeficient patients<ref>Fine HA, Mayer RJ. Primary central nervous system lymphoma. ''Ann Intern Med'' 1993; 119(11):1093-1104</ref> (such as those with AIDS and those iatrogenically immunosupressed) and does not have predilections for any age group. Mean [[CD4]]+ count at time of diagnosis is ~50/uL. Because of the severity of immunosuppression at the time of diagnosis, it is to no surprise that prognosis is usually poor.  In immunocompetent patients (that is, patients that do not have AIDS or some other immunodeficiency) there is rarely an association with EBV infection or other infectious DNAs. In the immunocompetent population, PCNSL typically affects older patients in their 50's and 60's.  Importantly, the incidence of PCNSL in the immunocompetent population has been reported to have increased more than 10-fold from 2.5 cases to 30 cases per 10 million population<ref>Eby NL, Grufferman S, Flannelly CM, Schold SC, Jr., Vogel FS, Burger PC. Increasing incidence of primary brain lymphoma in the US. ''Cancer'' 1988;62(11):2461-2465</ref><ref>Corn BW, Marcus SM, Topham A, Hauck W, Curran WJ, Jr. Will primary central nervous system lymphoma be the most frequent brain tumor diagnosed in the year 2000? ''Cancer'' 1997;79(12):2409-2413</ref>.  The cause for the increase in incidence of this disease in the immunocompetent population is unknown.
Please help WikiDoc by adding more content here.  It's easy!  Click  [[Help:How_to_Edit_a_Page|here]]  to learn about editing.


==References==
==References==
<references/>
{{Reflist|2}}
[[Category:Neurology]]
[[Category:Neurology]]
[[Category:Neurosurgery]]
[[Category:Neurosurgery]]
Line 11: Line 11:
[[Category:Viral diseases]]
[[Category:Viral diseases]]
[[Category:Oncology]]
[[Category:Oncology]]
[[Category:Disease]]
[[Category:Needs content]]


[[id:Limfoma susunan saraf pusat]]
[[id:Limfoma susunan saraf pusat]]
{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}

Revision as of 06:42, 17 September 2012

Primary central nervous system lymphoma Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Primary Central Nervous System Lymphoma from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Staging

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Primary central nervous system lymphoma pathophysiology On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Primary central nervous system lymphoma pathophysiology

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Primary central nervous system lymphoma pathophysiology

CDC on Primary central nervous system lymphoma pathophysiology

Primary central nervous system lymphoma pathophysiology in the news

Blogs on Primary central nervous system lymphoma pathophysiology

Directions to Hospitals Treating Primary central nervous system lymphoma

Risk calculators and risk factors for Primary central nervous system lymphoma pathophysiology

Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.

References

id:Limfoma susunan saraf pusat

Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Primary_central_nervous_system_lymphoma_pathophysiology&oldid=739122"