Autism future or investigational therapies: Difference between revisions
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==Future or Investigational Therapies== | ==Future or Investigational Therapies== | ||
Although many [[Alternative therapies for developmental and learning disabilities|alternative therapies and interventions]] are available, few are supported by scientific studies. | Although many [[Alternative therapies for developmental and learning disabilities|alternative therapies and interventions]] are available, few are supported by scientific studies.<ref>Lack of support for interventions: | ||
*{{cite journal |journal= Dev Med Child Neurol |date=2005 |volume=47 |issue=7 |pages=493–9 |title= Autism interventions: a critical update |author= Francis K |doi=10.1017/S0012162205000952 |pmid=15991872 |url=http://journals.cambridge.org/production/action/cjoGetFulltext?fulltextid=313204 |format=PDF}} | *{{cite journal |journal= Dev Med Child Neurol |date=2005 |volume=47 |issue=7 |pages=493–9 |title= Autism interventions: a critical update |author= Francis K |doi=10.1017/S0012162205000952 |pmid=15991872 |url=http://journals.cambridge.org/production/action/cjoGetFulltext?fulltextid=313204 |format=PDF}} | ||
*{{cite journal |journal= J Autism Dev Disord |date=2008 |volume=38 |issue=2 |pages=353–61 |title= Social skills interventions for children with Asperger's syndrome or high-functioning autism: a review and recommendations |author= Rao PA, Beidel DC, Murray MJ |doi=10.1007/s10803-007-0402-4 |pmid=17641962}} | *{{cite journal |journal= J Autism Dev Disord |date=2008 |volume=38 |issue=2 |pages=353–61 |title= Social skills interventions for children with Asperger's syndrome or high-functioning autism: a review and recommendations |author= Rao PA, Beidel DC, Murray MJ |doi=10.1007/s10803-007-0402-4 |pmid=17641962}} | ||
*{{cite journal |journal= Pediatr Ann |year=2007 |volume=36 |issue=8 |pages=497–8, 500–2, 504–5 |title= Scientifically unsupported therapies in the treatment of young children with autism spectrum disorders |author= Schechtman MA |pmid=17849608 |url=http://www.pediatricannalsonline.com/showPdf.asp?rID=23083 |format=PDF}} | *{{cite journal |journal= Pediatr Ann |year=2007 |volume=36 |issue=8 |pages=497–8, 500–2, 504–5 |title= Scientifically unsupported therapies in the treatment of young children with autism spectrum disorders |author= Schechtman MA |pmid=17849608 |url=http://www.pediatricannalsonline.com/showPdf.asp?rID=23083 |format=PDF}} | ||
Treatment approaches have little empirical support in [[quality of life|quality-of-life]] contexts, and many programs focus on success measures that lack predictive validity and real-world relevance. Scientific evidence appears to matter less to service providers than program marketing, training availability, and parent requests.<ref>{{cite journal |journal= Focus Autism Other Dev Disabl |date=2005 |volume=20 |issue=2 |pages=66–79 |title= Early intervention practices for children with autism: descriptions from community providers |author= Stahmer AC, Collings NM, Palinkas LA |pmid=16467905 |pmc=1350798}}</ref> Although most alternative treatments, such as [[melatonin]], have only mild adverse effects,<ref>{{cite journal |journal= Aust Fam Physician |year=2007 |volume=36 |issue=10 |pages=827–30 |title= Children and autism—part 2—management with complementary medicines and dietary interventions |author= Angley M, Semple S, Hewton C, Paterson F, McKinnon R |pmid=17925903 |url=http://www.racgp.org.au/Content/NavigationMenu/Publications/AustralianFamilyPhys/2007issues/afp200710/200710angley.pdf |format=PDF}}</ref> a 2008 study found that autistic boys on [[Casein#Casein-free_diet|casein-free diets]] have significantly thinner bones,<ref>{{cite journal |journal= J Autism Dev Disord |date=2008 |volume=38 |issue=5 |pages=848–56 |title= Reduced bone cortical thickness in boys with autism or autism spectrum disorder |author= Hediger ML, England LJ, Molloy CA, Yu KF, Manning-Courtney P, Mills JL |doi=10.1007/s10803-007-0453-6 |pmid=17879151 |laysummary=http://www.nih.gov/news/health/jan2008/nichd-29.htm |laysource= NIH News |laydate=2008-01-29}}</ref> and botched [[chelation therapy]] killed a five-year-old autistic boy in 2005.<ref>{{cite journal |journal=Pediatrics |date=2006 |volume=118 |issue=2 |pages=e534-6 |title= Deaths resulting from hypocalcemia after administration of edetate disodium: 2003–2005 |author= Brown MJ, Willis T, Omalu B, Leiker R |doi=10.1542/peds.2006-0858 |pmid=16882789 |url=http://pediatrics.aappublications.org/cgi/content/full/118/2/e534}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:07, 29 August 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Future or Investigational Therapies
Although many alternative therapies and interventions are available, few are supported by scientific studies. Although most alternative treatments, such as melatonin, have only mild adverse effects,[1] a 2008 study found that autistic boys on casein-free diets have significantly thinner bones,[2] and botched chelation therapy killed a five-year-old autistic boy in 2005.[3]
References
- ↑ Angley M, Semple S, Hewton C, Paterson F, McKinnon R (2007). "Children and autism—part 2—management with complementary medicines and dietary interventions" (PDF). Aust Fam Physician. 36 (10): 827–30. PMID 17925903.
- ↑ Hediger ML, England LJ, Molloy CA, Yu KF, Manning-Courtney P, Mills JL (2008). "Reduced bone cortical thickness in boys with autism or autism spectrum disorder". J Autism Dev Disord. 38 (5): 848–56. doi:10.1007/s10803-007-0453-6. PMID 17879151. Lay summary – NIH News (2008-01-29).
- ↑ Brown MJ, Willis T, Omalu B, Leiker R (2006). "Deaths resulting from hypocalcemia after administration of edetate disodium: 2003–2005". Pediatrics. 118 (2): e534–6. doi:10.1542/peds.2006-0858. PMID 16882789.