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==Overview==
==Overview==
'''Barrett's esophagus''' refers to an abnormal change ([[metaplasia]]) in the cells of the lower end of the [[esophagus]] thought to be caused by damage from chronic acid exposure, or [[reflux esophagitis]].<ref name=Stein_1993>{{cite journal |author=Stein H, Siewert J |title=Barrett's esophagus: pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management |journal=Dysphagia |volume=8 |issue=3 |pages=276-88 |year=1993 |pmid=8359051}}</ref> Barrett's esophagus is found in about 10% of patients who seek medical care for heartburn ([[gastroesophageal reflux]]). It is considered to be a [[premalignant condition]] and is associated with an increased risk of [[esophageal cancer]].<ref name=Koppert_2005>{{cite journal |author=Koppert L, Wijnhoven B, van Dekken H, Tilanus H, Dinjens W |title=The molecular biology of esophageal adenocarcinoma |journal=J Surg Oncol |volume=92 |issue=3 |pages=169-90 |year=2005 |pmid=16299787}}</ref>
'''Barrett's esophagus''' refers to an abnormal change ([[metaplasia]]) in the cells of the lower end of the [[esophagus]] thought to be caused by damage from chronic acid exposure, or [[reflux esophagitis]].<ref name=Stein_1993>{{cite journal |author=Stein H, Siewert J |title=Barrett's esophagus: pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management |journal=Dysphagia |volume=8 |issue=3 |pages=276-88 |year=1993 |pmid=8359051}}</ref> It is a condition in which abnormal columnar epithelium replaces the normal squamous epithelium in the distal esophagus.


==References==
==References==

Revision as of 13:17, 29 August 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Barrett's esophagus refers to an abnormal change (metaplasia) in the cells of the lower end of the esophagus thought to be caused by damage from chronic acid exposure, or reflux esophagitis.[1] It is a condition in which abnormal columnar epithelium replaces the normal squamous epithelium in the distal esophagus.

References

  1. Stein H, Siewert J (1993). "Barrett's esophagus: pathogenesis, epidemiology, functional abnormalities, malignant degeneration, and surgical management". Dysphagia. 8 (3): 276–88. PMID 8359051.

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