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==Historical perspective==
==Historical perspective==
The link between age-related reductions in bone density and fracture risk goes back at least to Astley Cooper, and the term "osteoporosis" and recognition of its pathological appearance is generally attributed to the French pathologist Lobstein.<ref>Lobstein JGCFM. ''Lehrbuch der pathologischen Anatomie.'' Stuttgart: Bd II, 1835.</ref> The American endocrinolgist Fuller Albright linked osteoporosis with the postmenopausal state.<ref>{{cite journal | author=Albright F, Bloomberg E, Smith PH|year=1940 |month= |title= Postmenopausal osteoporosis |journal=Trans. Assoc. Am. Physicians. |volume=55 |pages=298-305}}</ref>Bisphosponates, which revolutionized the treatment of osteoporosis, were discovered in the 1960s.<ref>{{cite journal|author=Patlak M |title=Bone builders: the discoveries behind preventing and treating osteoporosis |journal=FASEB J. |volume=15|issue=10 |pages=1677E–E |year=2001 |pmid=11481214 |doi=}}</ref>
* The link between age-related reductions in bone density and fracture risk goes back at least to Astley Cooper, and the term "osteoporosis" and recognition of its pathological appearance is generally attributed to the French pathologist Lobstein.<ref>Lobstein JGCFM. ''Lehrbuch der pathologischen Anatomie.'' Stuttgart: Bd II, 1835.</ref>  
 
* The American endocrinolgist Fuller Albright linked osteoporosis with the postmenopausal state.<ref>{{cite journal | author=Albright F, Bloomberg E, Smith PH|year=1940 |month= |title= Postmenopausal osteoporosis |journal=Trans. Assoc. Am. Physicians. |volume=55 |pages=298-305}}</ref>
 
* Bisphosponates, which revolutionized the treatment of osteoporosis, were discovered in the 1960s.<ref>{{cite journal|author=Patlak M |title=Bone builders: the discoveries behind preventing and treating osteoporosis |journal=FASEB J. |volume=15|issue=10 |pages=1677E–E |year=2001 |pmid=11481214 |doi=}}</ref>


==References==
==References==

Revision as of 15:18, 20 July 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Raviteja Guddeti, M.B.B.S. [2]

Overview

Historical perspective

  • The link between age-related reductions in bone density and fracture risk goes back at least to Astley Cooper, and the term "osteoporosis" and recognition of its pathological appearance is generally attributed to the French pathologist Lobstein.[1]
  • The American endocrinolgist Fuller Albright linked osteoporosis with the postmenopausal state.[2]
  • Bisphosponates, which revolutionized the treatment of osteoporosis, were discovered in the 1960s.[3]

References

  1. Lobstein JGCFM. Lehrbuch der pathologischen Anatomie. Stuttgart: Bd II, 1835.
  2. Albright F, Bloomberg E, Smith PH (1940). "Postmenopausal osteoporosis". Trans. Assoc. Am. Physicians. 55: 298–305.
  3. Patlak M (2001). "Bone builders: the discoveries behind preventing and treating osteoporosis". FASEB J. 15 (10): 1677E–E. PMID 11481214.




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