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==Overview==
==Overview==
Progression of [[aortic sclerosis]] to [[aortic stenosis]] has been suggested as a marker of increased cardiovascular risk, including increased mortality.
Calcification of the aortic valve is common among the elderly population and shares epidemiologic and histopathologic similarities to [[atherosclerosis]].<ref name="pmid20185020">{{cite journal |author=Owens DS, Katz R, Takasu J, Kronmal R, Budoff MJ, O'Brien KD |title=Incidence and progression of aortic valve calcium in the Multi-ethnic Study of Atherosclerosis (MESA) |journal=[[The American Journal of Cardiology]] |volume=105 |issue=5 |pages=701–8 |year=2010 |month=March |pmid=20185020 |pmc=2829478 |doi=10.1016/j.amjcard.2009.10.071 |url=http://linkinghub.elsevier.com/retrieve/pii/S0002-9149(09)02766-0 |accessdate=2012-04-11}}</ref> Furthermore, progression of [[aortic sclerosis]] to [[aortic stenosis]] has also been associated with an increase cardiovascular risk, including increased mortality.


==Progression to Aortic Stenosis==
==Progression to Aortic Stenosis==

Revision as of 13:42, 11 April 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Lakshmi Gopalakrishnan, M.B.B.S. [2]

Overview

Calcification of the aortic valve is common among the elderly population and shares epidemiologic and histopathologic similarities to atherosclerosis.[1] Furthermore, progression of aortic sclerosis to aortic stenosis has also been associated with an increase cardiovascular risk, including increased mortality.

Progression to Aortic Stenosis

Echocardiographic indicators of progression of aortic sclerosis to aortic stenosis include:

  • Restricted leaflet mobility
  • Increased echogenicity suggestive of increase leaflet calcification
  • Increase in jet flow velocity across the valve

References

  1. Owens DS, Katz R, Takasu J, Kronmal R, Budoff MJ, O'Brien KD (2010). "Incidence and progression of aortic valve calcium in the Multi-ethnic Study of Atherosclerosis (MESA)". The American Journal of Cardiology. 105 (5): 701–8. doi:10.1016/j.amjcard.2009.10.071. PMC 2829478. PMID 20185020. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)

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