Diabetic foot natural history, complications and prognosis: Difference between revisions
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Revision as of 21:21, 29 July 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Vishnu Vardhan Serla M.B.B.S. [2] Usama Talib, BSc, MD [3]
Overview
Patients with diabetic foot have an increased risk of all-cause mortality, especially cardiovascular disorders, compared with patients with diabetes without a history of diabetic foot ulcer. The complications of diabetic foot ulcers include infection, sepsis, osteomyelitis and death.[1][2]
Natural History
If left untreated diabetic ulcer may progress to infection, sepsis, or osteomyelitis. According to an estimate 20% of significant diabetic foot ulcers end up requiring an amputation. Untreated diabetic foot ulcer cab lead to death of the affected individual.[2]
Complications
Diabetic foot ulcer can cause many complications including:[2]
- Infection
- Sepsis
- Osteomyelitis
- Gangrene
- Death
Prognosis
If left untreated death is the outcome. The 5 year risk of mortality in diabetic patients with a foot ulcer is 2.5 times higher than diabetic individuals without a foot ulcer.[2]
References
- ↑ Brownrigg JR, Davey J, Holt PJ, Davis WA, Thompson MM, Ray KK; et al. (2012). "The association of ulceration of the foot with cardiovascular and all-cause mortality in patients with diabetes: a meta-analysis". Diabetologia. 55 (11): 2906–12. doi:10.1007/s00125-012-2673-3. PMID 22890823.
- ↑ 2.0 2.1 2.2 2.3 Armstrong DG, Boulton AJM, Bus SA (2017). "Diabetic Foot Ulcers and Their Recurrence". N Engl J Med. 376 (24): 2367–2375. doi:10.1056/NEJMra1615439. PMID 28614678.