Oligodendroglioma other diagnostic studies: Difference between revisions
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'''Indications for different types of biopsies''' | |||
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Type of biopsy}} | ! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Type of biopsy}} | ||
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[[craniotomy|Open biopsy]] | [[craniotomy|Open biopsy]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Surgically resectable masses | *[[Surgery|Surgically]] [[Resection|resectable]] [[Mass|masses]] | ||
*Lesions in accessible and relatively | *[[Lesions]] in [[Accessible image|accessible]] and [[Relatively compact|relatively]] “[[Silent News|silent]]” [[Area|areas]] of the [[brain]] or in [[Area|areas]] of the [[brain]] with a mild postoperative [[Neurological|neurologic]] deficit | ||
*Appearance consistent with [[tumor]] on the [[MRI]] | *[[Appearance]] consistent with [[tumor]] on the [[MRI]] | ||
*Large [[tumors]] exerting mass effect | *Large [[tumors]] exerting [[mass effect]] | ||
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| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | | style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" | | ||
[[Stereotactic|Stereotactic biopsy]] | [[Stereotactic|Stereotactic biopsy]] | ||
| style="padding: 5px 5px; background: #F5F5F5;" | | | style="padding: 5px 5px; background: #F5F5F5;" | | ||
*Deep-seated [[tumor]] that is not amenable to resection | *Deep-seated [[tumor]] that is not amenable to [[resection]] | ||
*Lesions in which the radiological and clinical findings are ambiguous | *[[Lesions]] in which the [[radiological]] and [[clinical]] findings are ambiguous | ||
*Diffuse or multiple lesions | *[[Diffuse]] or multiple [[lesions]] | ||
*Appearance that suggests a [[lymphoma]], which would not require resection | *[[Appearance]] that [[Suggestion|suggests]] a [[lymphoma]], which would not require [[resection]] | ||
*Change in the appearance of a previously diagnosed or treated [[tumor]] | *[[Change detection|Change]] in the [[appearance]] of a previously [[Diagnose|diagnosed]] or [[Treatments|treated]] [[tumor]] | ||
*Assessment of tumor after treatment (to distinguish between [[radiation|radiation necrosis]] and tumor recurrence) | *[[Assessment and Plan|Assessment]] of [[tumor]] after [[Treatments|treatment]] (to distinguish between [[radiation|radiation necrosis]] and [[tumor]] [[Recurrence plot|recurrence]]) | ||
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Revision as of 23:36, 18 May 2019
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Oligodendroglioma Microchapters |
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Oligodendroglioma other diagnostic studies On the Web |
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American Roentgen Ray Society Images of Oligodendroglioma other diagnostic studies |
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Risk calculators and risk factors for Oligodendroglioma other diagnostic studies |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sara Mohsin, M.D.[2]Sujit Routray, M.D. [3]
Overview
Other diagnostic studies for oligodendroglioma include biopsy (homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus and perinuclear halo) and fluorescent in-situ hybridization (FISH) technique (deletions of chromosome 1p and 19q).
Other Diagnostic Studies
Biopsy
- Biopsy may be performed to help confirm the diagnosis of oligodendroglioma
- On biopsy, oligodendroglioma is characterized by homogeneous, compact, rounded cells with distinct borders and clear cytoplasm surrounding a dense central nucleus and perinuclear halo, giving it the characteristic “fried egg” appearance[1]
- Biopsy may be done at the time of surgical resection of oligodendroglioma
- Biopsy may be of two types:
- Indications for open biopsy and stereotactic biopsy are described below:[2]
| Type of biopsy | Indications |
|---|---|
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Fluorescent in-situ hybridization (FISH) technique
- FISH demonstrates deletions of chromosome 1p and 19q[3]
References
- ↑ Wesseling P, van den Bent M, Perry A (2015). "Oligodendroglioma: pathology, molecular mechanisms and markers". Acta Neuropathol. 129 (6): 809–27. doi:10.1007/s00401-015-1424-1. PMC 4436696. PMID 25943885.
- ↑ Eskandar EN, Loeffler JS, O'Neill AM, Hunter GJ, Louis DN (2004). "Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 33-2004. A 34-year-old man with a seizure and a frontal-lobe brain lesion". N Engl J Med. 351 (18): 1875–82. doi:10.1056/NEJMcpc049025. PMID 15509821.
- ↑ Ersen, Ayca (2008), Pathology of malignant gliomas: Challenges of everyday practice and the WHO 2007, Turkish Journal of Pathology, retrieved 9 October, 2015 Check date values in:
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