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| {{familytree/start |summary=PE diagnosis Algorithm.}} | | |
| {{familytree | | | | | | | | | | A02 | | | | | |A02=Malignant germ cell tumor}} | | |
| {{familytree | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|-|.| | | | | | }} | | |
| {{familytree | | | C01 | | | | | | | | | | | | | C02 | | |C01=Prior surgery|C02=Initial surgery}} | | |
| {{familytree | |,|-|^|-|.| | | | | | | | | | |,|-|^|-|.| | }} | | {{Family tree/start}} |
| {{familytree | D01 | | D02 | | | | | | | | | D03 | | D04 |D01=Complete staging|D02=Incomplete staging|D03=Fertility sparing prefered|D04=Fertility sparing not prefered}} | | {{Family tree | | | | | | | | A01 | | | |A01= Patient with neck mass suspected to carotid body tumor}} |
| {{familytree | |!| | | |!| | | | | | | | | | |!| | | |!| | }}
| | {{Family tree | | | | | | | | |!| | | | | }} |
| {{familytree | E01 | | E02 | | | | | | | | | E03 | | E04 |E01=Treatment based<br>on<br>the staging|E02=Imaging:<br>Chest/<br>abdomen/<br>pelvis CT with contrast|E03=Fertility sparing surgery<br>and<br>complete staging|E04=Surgery to stage}}
| | {{Family tree | | | | | | | | B01 | | | |B01= History, Physical examination, and evaluation of cnotralateral side}} |
| {{familytree | | | | | |!| | | | | | | | | | |!| | | |!| | | | }} | | {{Family tree | | | | | |,|-|-|^|-|-|.| | }} |
| {{familytree | | | | | |!| | | | | | | | | | |`| F02 |'| | | |F02=Treatment based on the staging and pathology of tumor}} | | {{Family tree | | | | | C01 | | | | C02 |C01= Patients with age < 50 years<br>Patients with multiple paraganglioma<br>Patients with a positive family history| C02= The rest of the patients}} |
| {{familytree | | | |,|-|^|-|-|-|-|-|-|-|.| | | | | | | }} | | {{Family tree | | | | | |!| | | | | }} |
| {{familytree | | | G01 | | | | | | | | G02 | | | | | | | | | | | | | | |G01=Yolk sac tumor<br>grade2-3 immature teratoma,<br>non-gestational choriocarcinoma<br>or mixed histology|G02=Dysgerminoma<br>or<br>grade 1 immature teratoma|L03=Dysgerminoma or grade 1 immature teratoma}} | | {{Family tree | | | | | D01 | | | |D01= SDHD genetic testing} |
| {{familytree | | | |!| | | | | | | | | |!| | | | | | | | | | | | }} | | {{Family tree | | |,|-|-|^|-|-|.| | }} |
| {{familytree | | | |!| | | | | |,|-|-|-|+|-|-|-|.|}} | | {{Family tree | | E01 | | | | E02 |E01= Presence of SDHD mutation |E02= Absence of SDHD mutation}} |
| {{familytree | | | |!| | | | | I02 | | I03 | | I04 | |I02=Imaging and tumor markers<br>are<br>positive|I03=Negative imaging<br>and<br>positive tumor markers|I04=Negative imaging<br>and<br>negative or positive tumor markers}}
| | {{Family tree | | | | | | | | |!| | | | | }} |
| {{familytree | | | |!| | | | | |!| | | |!| | | |!| | | |}} | | {{Family tree | | | | | | | | F01 | | | |F01= SDHC and SDHB genetic testing} |
| {{familytree | |,|-|^|-|.| | | K03 | | K04 | | K05 | | |K03=Decide according to fertility sparing preference<br>and/or pathologic finding<br>for surgery and<br>further adjuant therapy|K04=Observe|K05=Observe|}}
| | {{Family tree | | | | | |,|-|-|^|-|-|.| | }} |
| {{familytree | J01 | | J02 | | | | | | | | | | | | | | | | | | |J01=Imaging and tumor markers<br>are<br>positive|J02=Negative imaging<br>and<br>negative and positive tumor markers}} | | {{Family tree | | | | | G01 | | | | G02 |G01= Presence of SDHC/B mutation |G02= Absence of SDHC/B mutation}} |
| {{familytree | |!| | | | | | | | | | | | | | | | | | | | | |}}
| | {{Family tree/end}} |
| {{familytree | K01 | | | | | | | | | | | | | | | | | | | |K01=Decide<br>according to<br>fertility sparing preference<br>for surgery and further chemotherapy|}}
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| {{familytree | | | | | | | | | | | | | | | | | | | | | | | |}}
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| {{familytree | | | | | | | | | | | | | | | | | | | | | | | |}}
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| {{familytree/end}} | |
{{Family tree | | | | | D01 | | | |D01= SDHD genetic testing}
{{Family tree | | | | | | | | F01 | | | |F01= SDHC and SDHB genetic testing}
| | | | | | | Patient with neck mass suspected to carotid body tumor | | | |
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| | | | | | | History, Physical examination, and evaluation of cnotralateral side | | | |
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| | | | | | | |
| | | | Patients with age < 50 years Patients with multiple paraganglioma Patients with a positive family history | | | | The rest of the patients |
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| Presence of SDHD mutation | | | | Absence of SDHD mutation |
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| | | | Presence of SDHC/B mutation | | | | Absence of SDHC/B mutation |