Leiomyosarcoma history and symptoms: Difference between revisions

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== Overview ==
== Overview ==
The majority of patients with [[leiomyosarcoma]] remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, [[weight loss]], a general feeling of ill health (malaise), and nausea and [[vomiting]], GI bleeding, metastasis.  
The majority of patients with [[leiomyosarcoma]] remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, [[weight loss]], nausea and [[vomiting]], vaginal bleeding, vaginal discharge, feeling of pressure in abdomen or pelvic, painless growing lump in abdomen or pelvic cavity.  


==History and Symptoms==
==History and Symptoms==

Revision as of 15:26, 7 March 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

The majority of patients with leiomyosarcoma remain asymptomatic for decades. General symptoms associated with cancer may occur including fatigue, fever, weight loss, nausea and vomiting, vaginal bleeding, vaginal discharge, feeling of pressure in abdomen or pelvic, painless growing lump in abdomen or pelvic cavity.

History and Symptoms

The symptoms of leiomyosarcoma depend on the location of the tumor. For the tumors always develop in gastrointestinal tract and uterus, usual symptoms are the following.[1][2][3][4][5]

  • Irregular vaginal bleeding (Intermenstrual or postmenopausal)
  • A new lump or a lump that is protruding into vagina or growing mass in abdomen or pelvic.
  • Pelvic pain in uterine leiomyosarcoma
  • Dysphagia in esophageal leiomyosarcoma
  • Black, tarry stools or rectal bleeding in rectal leiomyosarcoma

References

  1. Zhang BH, Zhang HT, Wang YG (2014) Esophageal leiomyosarcoma: clinical analysis and surgical treatment of 12 cases. Dis Esophagus 27 (6):547-51. DOI:10.1111/j.1442-2050.2012.01444.x PMID: 23163522
  2. Hartman DS, Hayes WS, Choyke PL, Tibbetts GP (1992) From the archives of the AFIP. Leiomyosarcoma of the retroperitoneum and inferior vena cava: radiologic-pathologic correlation. Radiographics 12 (6):1203-20. DOI:10.1148/radiographics.12.6.1439022 PMID: 1439022
  3. Jideh B, Yang T, Turner I (2017) Rectal Bleeding Due to Leiomyosarcoma. Clin Gastroenterol Hepatol 15 (1):e1-e2. DOI:10.1016/j.cgh.2016.08.008 PMID: 27530097
  4. Liao Q, Wang J, Han J (2001) [Clinical and pathological analysis on 106 cases with uterine sarcoma.] Zhonghua Fu Chan Ke Za Zhi 36 (2):104-7. PMID: 11783345
  5. Sahli, N.; Khmou, M.; Khalil, J.; Elmajjaoui, S.; El Khannoussi, B.; Kebdani, T.; Elkacemi, H.; Benjaafar, N. (2016). "Unusual evolution of leiomyosarcoma of the rectum: a case report and review of the literature". Journal of Medical Case Reports. 10 (1). doi:10.1186/s13256-016-1047-8. ISSN 1752-1947.


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