Rhabdomyosarcoma staging: Difference between revisions

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==Staging of rhabdomyosarcoma==
==Staging of rhabdomyosarcoma==
* There are two staging classification for rhabdomyosarcoma:<ref name="pmid2407808">{{cite journal| author=Crist WM, Garnsey L, Beltangady MS, Gehan E, Ruymann F, Webber B et al.| title=Prognosis in children with rhabdomyosarcoma: a report of the intergroup rhabdomyosarcoma studies I and II. Intergroup Rhabdomyosarcoma Committee. | journal=J Clin Oncol | year= 1990 | volume= 8 | issue= 3 | pages= 443-52 | pmid=2407808 | doi=10.1200/JCO.1990.8.3.443 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2407808  }} </ref><ref name="pmid2407808">{{cite journal| author=Crist WM, Garnsey L, Beltangady MS, Gehan E, Ruymann F, Webber B et al.| title=Prognosis in children with rhabdomyosarcoma: a report of the intergroup rhabdomyosarcoma studies I and II. Intergroup Rhabdomyosarcoma Committee. | journal=J Clin Oncol | year= 1990 | volume= 8 | issue= 3 | pages= 443-52 | pmid=2407808 | doi=10.1200/JCO.1990.8.3.443 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2407808  }} </ref>
* There are two staging classification for rhabdomyosarcoma:<ref name="pmid2407808">{{cite journal| author=Crist WM, Garnsey L, Beltangady MS, Gehan E, Ruymann F, Webber B et al.| title=Prognosis in children with rhabdomyosarcoma: a report of the intergroup rhabdomyosarcoma studies I and II. Intergroup Rhabdomyosarcoma Committee. | journal=J Clin Oncol | year= 1990 | volume= 8 | issue= 3 | pages= 443-52 | pmid=2407808 | doi=10.1200/JCO.1990.8.3.443 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2407808  }} </ref>
** Clinical group (CG)
** Clinical group (CG)
*** Created by intergroup rhabdomyosarcoma study group (IRSG) in 1972
*** Created by intergroup rhabdomyosarcoma study group (IRSG) in 1972

Revision as of 15:54, 1 February 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]

Overview

According to the Children's Oncology Group, there are four stages of rhabdomyosarcoma based on the location of tumor, size of tumor, involvement of lymph nodes, and metastasis.

Staging of rhabdomyosarcoma

  • There are two staging classification for rhabdomyosarcoma:[1]
    • Clinical group (CG)
      • Created by intergroup rhabdomyosarcoma study group (IRSG) in 1972
      • Based on spread of tumor cells at diagnosis and remaining disease after surgery
      • Categorized in four groups
    • Tumor, node, metastasis system (TNM)
      • Based on tumor size, node involvement, and metastasis
      • Categorized in four groups
Clinical group staging[2]
Stage Description
I
  • Contain 13% of all cases
  • Localized region
  • Complete resection
  • No nodal involvement
II
  • Contain 20% of all cases
  • IIA group: Complete resection with microscopic residual disease/ no nodal involvement
  • IIB group: Complete resection with no microscopic residual diseases/ regional nodal involvement
  • IIC group: Complete resection with microscopic residual disease/ regional nodal involvement
III
  • Contain 48% of all cases
  • Incomplete resection or biopsy
  • Gross residual disease
IV
  • Contain 18% of all cases
  • Distant metastasis at time of diagnosis

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References

  1. Crist WM, Garnsey L, Beltangady MS, Gehan E, Ruymann F, Webber B; et al. (1990). "Prognosis in children with rhabdomyosarcoma: a report of the intergroup rhabdomyosarcoma studies I and II. Intergroup Rhabdomyosarcoma Committee". J Clin Oncol. 8 (3): 443–52. doi:10.1200/JCO.1990.8.3.443. PMID 2407808.
  2. Crist W, Gehan EA, Ragab AH, Dickman PS, Donaldson SS, Fryer C; et al. (1995). "The Third Intergroup Rhabdomyosarcoma Study". J Clin Oncol. 13 (3): 610–30. doi:10.1200/JCO.1995.13.3.610. PMID 7884423.

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