Sandbox:Shadan: Difference between revisions
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| Line 63: | Line 63: | ||
**Lymph node origin | **Lymph node origin | ||
***Inflammatory lymoh nodes | ***Inflammatory lymoh nodes | ||
== Risk factors== | |||
Associated risk factors leading to female breast cancer: | |||
* Age: probability of breast cancer from birth to 39 years; 1 in 202, from 40 to 59 years; 1 in 26, from 60 to 69 years; 1 in 28. | |||
*Personal history of breast cancer | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 18:38, 6 December 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Classification
Classification of breast lumps based on epithelial hyperplasia[1]
- Approximately 65% of all benign breast disease considered as nonproliferative(NP)with relative cancer risk of 1.2, 1.4 times:
- Simple cyst
- Fibrosis
- Fibroadenoma (simple)
- Columnar alteration (Simple)
- Apocrine metaplasia (simple)
- Mild ductal hyperplasia
- Approximately 30% of total are classifed as proliferative disease(PD) with relative cancer risk of 1.7, 2.1 times
- Usual ductal hyperplasia
- Sclerosing adenosis
- Columnar hyperplasia
- papilloma
- Radical scar
- Approximately 5% to 8% of the rest regarded to PD with atypia with relative cancer risk more than 4 times
- Atypical lobar hyperplasia
- Lobular carcinoma in situ
- Atypical ductal hyperplasia
- Unclear risk
- Mucocele like tumor
- Apocrine atypia
- Secretory atypia
Classification of benign breast lesion regarding to histological region:
- Terminal and lobular ducts
- Acinar distention
- Cyst
- Intralobular connective tissue proliferation
- Sclerosing adenosis
- Fibroadenoma
- Phyllodes tumor
- Hamartoma
- Epithelial changes in terminal duct lobaular units (TDLU)
- Apocrine metaplasia
- Ductal and lobular hyperplasia, usual and typical
- Papillomatosis
- Intracystic papilloma
- Acinar distention
- Ductal system
- Ductal ectasia
- Intraductal papilloma
- Lesion of different origin
- Fatty tissue lesion
- Lipoma
- Liponecrosis
- Fibrous tissue lesions
- Focal fibrosis
- Diabetic mastopathy
- Pseudoangiomatous stromal hyperplasia (PASH)
- Myofibroblastoma
- Vascular origin
- Hemangioma
- Inflammatory origin
- Mastitis/abscess
- Tuberclosis and sarcoidosis
- Foreign body granuloma and siliconoma
- Lymph node origin
- Inflammatory lymoh nodes
- Fatty tissue lesion
Risk factors
Associated risk factors leading to female breast cancer:
- Age: probability of breast cancer from birth to 39 years; 1 in 202, from 40 to 59 years; 1 in 26, from 60 to 69 years; 1 in 28.
- Personal history of breast cancer
References
- ↑ Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K; et al. (2005). "Benign breast disease and the risk of breast cancer". N Engl J Med. 353 (3): 229–37. doi:10.1056/NEJMoa044383. PMID 16034008.