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==Classification== | ==Classification== | ||
'''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]''' | '''Classification of [[breast lumps]] based on [[epithelial hyperplasia]]<ref name="pmid16034008">{{cite journal| author=Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K et al.| title=Benign breast disease and the risk of breast cancer. | journal=N Engl J Med | year= 2005 | volume= 353 | issue= 3 | pages= 229-37 | pmid=16034008 | doi=10.1056/NEJMoa044383 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16034008 }} </ref>''' | ||
*Approximately 65% of all [[BBD]] considered as [[nonproliferative]](NP)with relative cancer risk of 1.2, 1.4 times: | *Approximately 65% of all [[BBD]] considered as [[nonproliferative]](NP)with relative cancer risk of 1.2, 1.4 times: | ||
**Simple cyst | **Simple cyst | ||
**Fibrosis | **Fibrosis | ||
*** Fibroadenoma (simple) | |||
**** Columnar alteration (Simple) | |||
***** Apocrine metaplasia (simple) | |||
****** Mild ductal hyperplasia | |||
** Approximately 30% of total are classifed as [[proliferative disease(PD) with relative cancer risk of 1.7, 2.1 times | |||
** Usual ductal hyperplasia | |||
*** Sclerosing adenosis | |||
**** Columnar hyperplasia | |||
***** papilloma | ***** papilloma | ||
****** Radical scar | ****** Radical scar | ||
Revision as of 16:17, 6 December 2018
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shadan Mehraban, M.D.[2]
Overview
Classification
Classification of breast lumps based on epithelial hyperplasia[1]
- Approximately 65% of all BBD considered as nonproliferative(NP)with relative cancer risk of 1.2, 1.4 times:
- Simple cyst
- Fibrosis
- Fibroadenoma (simple)
- Columnar alteration (Simple)
- Apocrine metaplasia (simple)
- Mild ductal hyperplasia
- Apocrine metaplasia (simple)
- Columnar alteration (Simple)
- Fibroadenoma (simple)
- Approximately 30% of total are classifed as [[proliferative disease(PD) with relative cancer risk of 1.7, 2.1 times
- Usual ductal hyperplasia
- Sclerosing adenosis
- Columnar hyperplasia
- Sclerosing adenosis
***** papilloma
****** Radical scar
*** Approximately 5% to 8% of the rest regarded to PD with atypiawith relative cancer risk more than 4 times
*** Atypical lobar hyperplasia
**** Lobular carcinoma in situ
***** Atypical ductal hyperplasia
**** Unclear risk
**** Mucocele like tumor
***** Apocrine atypia
****** Secretory atypia
References
- ↑ Hartmann LC, Sellers TA, Frost MH, Lingle WL, Degnim AC, Ghosh K; et al. (2005). "Benign breast disease and the risk of breast cancer". N Engl J Med. 353 (3): 229–37. doi:10.1056/NEJMoa044383. PMID 16034008.