Paroxysmal nocturnal hemoglobinuria history and symptoms: Difference between revisions

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{{CMG}}; {{AE}}  
{{CMG}}; {{AE}}  
==Overview==
==Overview==
==History and Symptoms==
==History and Symptoms==
===History===
===History===
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===Common Symptoms===
===Common Symptoms===
Common symptoms of [PNH] include:
Common symptoms of PNH include:
* Due to hemolysis   
* Due to hemolysis   
*# fatigue
*# Fatigue
*# dyspnea
*# Dyspnea
*# dark (red/pink/black) colored urine
*# Jaundice
*# jaundice


* Due to thrombosis
* Due to thrombosis:
*# headaches
*# Headaches
*# confusion
*# Confusion
*# abdominal pain
*# Abdominal pain
*# chest pain
*# Chest pain


* Due to nitric oxide depletion
* Due to [[nitric oxide]] depletion:
*# dysphagia
*# [[Dysphagia]]
*# chest pain from esophageal spasm
*# [[Chest pain]]
*# abdominal pain
*# [[Abdominal pain]]
*# erectile dysfunction
*# Erectile dysfunction


===Less Common Symptoms===
===Less Common Symptoms===
Less common symptoms of [PNH] include  
Less common symptoms of PNH include
* necrotic skin lesions
* [[Necrotic]] [[skin]] lesions
* abdominal fullness/ distension


==References==
==References==

Revision as of 19:13, 23 October 2018

Paroxysmal nocturnal hemoglobinuria Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Paroxysmal nocturnal hemoglobinuria from other Diseases

Epidemiology and Demographics

Risk Factors

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Natural History, Complications and Prognosis

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Diagnostic Study of Choice

History and Symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

History and Symptoms

History

Patients with PNH may have a positive history of:

  • Feeling tired/ weak
  • Shortness of breath
  • Dark colored urine
  • Jaundice
  • Blood clots
  • Difficulty swallowing
  • Chest pain
  • Abdominal pain
  • Headaches
  • Confusion
  • Dysphagia
  • Erectile dysfunction
  • Low blood cell counts
  • Iron deficiency

Common Symptoms

Common symptoms of PNH include:

  • Due to hemolysis
    1. Fatigue
    2. Dyspnea
    3. Jaundice
  • Due to thrombosis:
    1. Headaches
    2. Confusion
    3. Abdominal pain
    4. Chest pain

Less Common Symptoms

Less common symptoms of PNH include:

References

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