Paroxysmal nocturnal hemoglobinuria history and symptoms: Difference between revisions
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{{CMG}}; {{AE}} | {{CMG}}; {{AE}} | ||
==Overview== | ==Overview== | ||
==History and Symptoms== | ==History and Symptoms== | ||
===History=== | ===History=== | ||
Patients with | Patients with PNH may have a positive history of: | ||
* | * Feeling tired/ weak | ||
* | * Shortness of breath | ||
* | * Dark colored urine | ||
* | * Jaundice | ||
* | * Blood clots | ||
* | * Difficulty swallowing | ||
* | * Chest pain | ||
* | * Abdominal pain | ||
* | * Headaches | ||
* | * Confusion | ||
* | * Dysphagia | ||
* | * Erectile dysfunction | ||
* | * Low blood cell counts | ||
* | * Iron deficiency | ||
===Common Symptoms=== | ===Common Symptoms=== |
Revision as of 18:42, 23 October 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Overview
History and Symptoms
History
Patients with PNH may have a positive history of:
- Feeling tired/ weak
- Shortness of breath
- Dark colored urine
- Jaundice
- Blood clots
- Difficulty swallowing
- Chest pain
- Abdominal pain
- Headaches
- Confusion
- Dysphagia
- Erectile dysfunction
- Low blood cell counts
- Iron deficiency
Common Symptoms
Common symptoms of [PNH] include:
- Due to hemolysis
- fatigue
- dyspnea
- dark (red/pink/black) colored urine
- jaundice
- Due to thrombosis
- headaches
- confusion
- abdominal pain
- chest pain
- Due to nitric oxide depletion
- dysphagia
- chest pain from esophageal spasm
- abdominal pain
- erectile dysfunction
Less Common Symptoms
Less common symptoms of [PNH] include
- necrotic skin lesions
- abdominal fullness/ distension