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== Leiomyosarcoma classification ==
 
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Revision as of 06:01, 14 June 2018


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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

Leiomyosarcoma may be classified according to location of the tumor, prognosis and possible treatments into four group:

  • Leiomyosarcoma of Soft Tissue Retroperitoneal Somatic soft tissue
  • Leiomyosarcoma of Cutaneous Origin
  • Leiomyosarcoma of Vascular Origin (large vessel)
  • Leiomyosarcoma in the Immunocompromised Host
  • Leiomyosarcoma of Bone

While many staging systems exist for Leiomyosarcoma, the most commonly used system is the AJCC system.Leiomyosarcoma staging can also be done according to The Surgical Staging System of the Musculoskeletal Tumor Society (MSTS).Staging of leiomyosarcoma is important both in guiding treatment and in providing prognostic information.

Classification

Leiomyosarcoma may be classified according to location of the tumor, prognosis and possible treatments into four group:

  • Leiomyosarcoma of Soft Tissue Retroperitoneal Somatic soft tissue
  • Leiomyosarcoma of Cutaneous Origin
  • Leiomyosarcoma of Vascular Origin (large vessel)
  • Leiomyosarcoma in the Immunocompromised Host
  • Leiomyosarcoma of Bone

Staging

Although many staging system exist for the soft tissue sarcoma but the most commonly used system is the AJCC system.This system classifies the tumor based upon histological grade, the tumor size, location as superficial or deep, and the presence or absence of metastatic disease

Stage Histological Grade Size Location,

relative to fascia

Metastasis
IA Low < 5cm Superficial or Deep No
IB Low ≥ 5cm Superficial No
IIA Low ≥ 5cm Deep No
IIB High < 5cm Superficial or Deep No
IIC High ≥ 5cm Superficial No
III High ≥ 5cm Deep No
IV Any Any Any Yes

Leiomyosarcoma staging can also be done according to The Surgical Staging System of the Musculoskeletal Tumor Society (MSTS).This staging system classifies tumors as Ia, Ib, IIa, IIb, or III based upon the histologic grade of the tumor, its local extent and the presence or absences of macroscopic distant metastatic disease. If the tumor is localized to a single anatomic compartment, it is said to be confined. If it has spread locally beyond its initial compartment, then it is said to be unconfined.

Stage Histological

Grade

Local Extent of Disease Metastasis
Ia Low Confined No
Ib Low Unconfined No
IIa High Confined No
IIb High Unconfined No
III Any Any Yes

References

"Leiomyosarcoma Cancer: Diagnosis, Treatment, Research & Support".

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