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{{Tabes dorsalis}}
{{Tabes dorsalis}}
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==Overview==
==Overview==
'''Tabes dorsalis''' is a slow degeneration of the [[nerve cell]]s and nerve fibers that carry sensory information to the [[brain]]. The degenerating nerves are in the [[dorsal columns]] of the [[spinal cord]] (the portion closest to the back of the body) and carry information that help maintain a person's sense of position.
 
==Historical Perspective==
 
==Classification==
 
==Pathophysiology==


==Causes==
==Causes==
Tabes dorsalis is a form of [[neurosyphilis]], which is a complication of late or tertiary [[syphilis]] infection. Syphilis is a sexually transmitted, infectious disease. The infection damages the spinal cord and peripheral nervous tissue.
 
==Differentiating Hereditary pancreatitis from Other Diseases==


==Epidemiology and Demographics==
==Epidemiology and Demographics==
Tabes dorsalis is now very rare because syphilis is usually treated early in the disease.
 
==Risk Factors==
 
==Screening==
 
==Natural History, Complications, and Prognosis==
 


==Diagnosis==
==Diagnosis==
===CT===
===Diagnostic Study of Choice===
A head CT or a spine CT can be performed on the brain and spinal cord to help rule out other diseases.
 
===History and Symptoms===
 
===Physical Examination===
 
===Laboratory Findings===
 
===Electrocardiogram===
 
===X-ray===
 
===Echocardiography and Ultrasound===
 
===CT scan===


===MRI===
===MRI===
An [[MRI]] scan can be performed on the brain and spinal cord to help rule out other diseases.
 
===Other Imaging Findings===
 
===Other Diagnostic Studies===


==Treatment==
==Treatment==
===Medical Therapy===
===Medical Therapy===
[[Penicillin]], administered [[intravenous]]ly, is the treatment of choice. Associated pain can be treated with [[opiate]]s, [[valproate]], or [[carbamazepine]]. Patients may also require physical or rehabilitative therapy to deal with muscle wasting and weakness. Preventive treatment for those who come into sexual contact with an individual with tabes dorsalis is important.
==References==
{{Reflist|2}}


[[Category:Neurology]]
===Surgery===
 
===Primary Prevention===
 
===Secondary Prevention===


[[Category:Pain]]
==References==
{{reflist|2}}


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Revision as of 20:06, 16 February 2018

Tabes Dorsalis Microchapters

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Overview

Historical Perspective

Pathophysiology

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Differentiating Tabes Dorsalis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Mohamadmostafa Jahansouz M.D.[2]

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Hereditary pancreatitis from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications, and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT scan

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

References


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