Diaphragmatic hernia laboratory tests: Difference between revisions
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==Overview== | ==Overview== | ||
==== | ==Laboratory Findings== | ||
===Antenatal tests=== | |||
*[[Amniocentesis]]: [[Karyotype|karyotyping]] should be obtained to rule out associated [[chromosomal abnormalities]]. | |||
*[[Alpha-fetoprotein|Maternal alpha-fetoprotein]] is decreased in CDH<ref name="pmid26403792">{{cite journal |vauthors=McHoney M |title=Congenital diaphragmatic hernia, management in the newborn |journal=Pediatr. Surg. Int. |volume=31 |issue=11 |pages=1005–13 |year=2015 |pmid=26403792 |doi=10.1007/s00383-015-3794-9 |url=}}</ref> | |||
===Postnatal tests=== | |||
*[[Arterial blood gas]]: ABG may show [[hypoxemia]], [[metabolic acidosis]], and [[hypercapnia]]. | |||
*The infant should be investigated for the presence of associated [[chromosomal abnormalities]].<ref name="pmid1444648">{{cite journal |vauthors=Lally KP, Paranka MS, Roden J, Georgeson KE, Wilson JM, Lillehei CW, Breaux CW, Poon M, Clark RH, Atkinson JB |title=Congenital diaphragmatic hernia. Stabilization and repair on ECMO |journal=Ann. Surg. |volume=216 |issue=5 |pages=569–73 |year=1992 |pmid=1444648 |pmc=1242675 |doi= |url=}}</ref> | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
Revision as of 16:35, 22 December 2017
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Diaphragmatic hernia Main page |
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Diagnosis |
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Treatment |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Laboratory Findings
Antenatal tests
- Amniocentesis: karyotyping should be obtained to rule out associated chromosomal abnormalities.
- Maternal alpha-fetoprotein is decreased in CDH[1]
Postnatal tests
- Arterial blood gas: ABG may show hypoxemia, metabolic acidosis, and hypercapnia.
- The infant should be investigated for the presence of associated chromosomal abnormalities.[2]
References
- ↑ McHoney M (2015). "Congenital diaphragmatic hernia, management in the newborn". Pediatr. Surg. Int. 31 (11): 1005–13. doi:10.1007/s00383-015-3794-9. PMID 26403792.
- ↑ Lally KP, Paranka MS, Roden J, Georgeson KE, Wilson JM, Lillehei CW, Breaux CW, Poon M, Clark RH, Atkinson JB (1992). "Congenital diaphragmatic hernia. Stabilization and repair on ECMO". Ann. Surg. 216 (5): 569–73. PMC 1242675. PMID 1444648.