SFRS12: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{reflist}} +{{reflist|2}}, -<references /> +{{reflist|2}}, -{{WikiDoc Cardiology Network Infobox}} +))
 
m (Bot: HTTP→HTTPS)
 
Line 1: Line 1:
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{Underlinked|date=June 2016}}
{{PBB_Controls
{{Infobox_gene}}
| update_page = yes
'''Splicing factor, arginine/serine-rich 12''' is a [[protein]] that in humans is encoded by the ''SFRS12'' [[gene]].<ref name="pmid12043562">{{cite journal | vauthors = Zhang DL, Sun XJ, Ling LJ, Chen RS, Ma DL | title = [Molecular cloning, characterization, chromosomal assignment, genomic organization and verification of SFRS12(SRrp508), a novel member of human SR protein superfamily and a human homolog of rat SRrp86] | journal = Yi Chuan Xue Bao | volume = 29 | issue = 5 | pages = 377–83 |date=Jun 2002 | pmid = 12043562 | pmc =  | doi =  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140890| accessdate = }}</ref>
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = 
| image_source = 
| PDB =
| Name = Splicing factor, arginine/serine-rich 12
| HGNCid = 17882
| Symbol = SFRS12
| AltSymbols =; DKFZp564B176; MGC133045; SRrp508; SRrp86
| OMIM = 609268
| ECnumber = 
| Homologene = 10581
| MGIid = 2145245
| GeneAtlas_image1 = PBB_GE_SFRS12_212721_at_tn.png
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0003676 |text = nucleic acid binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}} {{GNF_GO|id=GO:0005681 |text = spliceosome}}
| Process = {{GNF_GO|id=GO:0006397 |text = mRNA processing}} {{GNF_GO|id=GO:0008380 |text = RNA splicing}}
  | Orthologs = {{GNF_Ortholog_box
    | Hs_EntrezGene = 140890
    | Hs_Ensembl = ENSG00000153914
    | Hs_RefseqProtein = NP_001070667
    | Hs_RefseqmRNA = NM_001077199
    | Hs_GenLoc_db =   
    | Hs_GenLoc_chr = 5
    | Hs_GenLoc_start = 65475802
    | Hs_GenLoc_end = 65515199
    | Hs_Uniprot = Q8WXA9
    | Mm_EntrezGene = 218543
    | Mm_Ensembl = ENSMUSG00000032621
    | Mm_RefseqmRNA = NM_172592
    | Mm_RefseqProtein = NP_766180
    | Mm_GenLoc_db = 
    | Mm_GenLoc_chr = 13
    | Mm_GenLoc_start = 104861997
    | Mm_GenLoc_end = 104884964
    | Mm_Uniprot = Q6P3Z1
  }}
}}
'''Splicing factor, arginine/serine-rich 12''', also known as '''SFRS12''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140890| accessdate = }}</ref>


<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
{{PBB_Summary
| section_title =  
| section_title =  
| summary_text = SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140890| accessdate = }}</ref>
| summary_text = SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM]<ref name="entrez">{{cite web | title = Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=140890| accessdate = }}</ref>
}}
}}


==References==
==References==
{{reflist|2}}
{{reflist}}
 
==Further reading==
==Further reading==
{{refbegin | 2}}
{{refbegin | 2}}
{{PBB_Further_reading  
{{PBB_Further_reading  
| citations =  
| citations =  
*{{cite journal | author=Ewing RM, Chu P, Elisma F, ''et al.'' |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  |pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 }}
*{{cite journal   |vauthors=Ewing RM, Chu P, Elisma F, etal |title=Large-scale mapping of human protein-protein interactions by mass spectrometry. |journal=Mol. Syst. Biol. |volume=3 |issue=  1|pages= 89 |year= 2007 |pmid= 17353931 |doi= 10.1038/msb4100134 | pmc=1847948 }}
*{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 | pmc=528928 }}
*{{cite journal | author=Heese K, Fujita M, Akatsu H, ''et al.'' |title=The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain. |journal=J. Mol. Neurosci. |volume=24 |issue= 2 |pages= 269-76 |year= 2005 |pmid= 15456940 |doi=  }}
*{{cite journal   |vauthors=Heese K, Fujita M, Akatsu H, etal |title=The splicing regulatory protein p18SRP is down-regulated in Alzheimer's disease brain. |journal=J. Mol. Neurosci. |volume=24 |issue= 2 |pages= 269–76 |year= 2005 |pmid= 15456940 |doi=10.1385/JMN:24:2:269 }}
*{{cite journal | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal   |vauthors=Ota T, Suzuki Y, Nishikawa T, etal |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
*{{cite journal | author=Li J, Hawkins IC, Harvey CD, ''et al.'' |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437-47 |year= 2003 |pmid= 14559993 |doi=  }}
*{{cite journal   |vauthors=Li J, Hawkins IC, Harvey CD, etal |title=Regulation of alternative splicing by SRrp86 and its interacting proteins. |journal=Mol. Cell. Biol. |volume=23 |issue= 21 |pages= 7437–47 |year= 2003 |pmid= 14559993 |doi=10.1128/MCB.23.21.7437-7447.2003  | pmc=207616 }}
*{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 | pmc=139241 }}
*{{cite journal | author=Peng R, Dye BT, Pérez I, ''et al.'' |title=PSF and p54nrb bind a conserved stem in U5 snRNA. |journal=RNA |volume=8 |issue= 10 |pages= 1334-47 |year= 2002 |pmid= 12403470 |doi=  }}
*{{cite journal   |vauthors=Peng R, Dye BT, Pérez I, etal |title=PSF and p54nrb bind a conserved stem in U5 snRNA. |journal=RNA |volume=8 |issue= 10 |pages= 1334–47 |year= 2002 |pmid= 12403470 |doi=10.1017/S1355838202022070  | pmc=1370341 }}
*{{cite journal  | author=Li J, Barnard DC, Patton JG |title=A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 39485-92 |year= 2002 |pmid= 12183448 |doi= 10.1074/jbc.M201784200 }}
*{{cite journal  | vauthors=Li J, Barnard DC, Patton JG |title=A unique glutamic acid-lysine (EK) domain acts as a splicing inhibitor. |journal=J. Biol. Chem. |volume=277 |issue= 42 |pages= 39485–92 |year= 2002 |pmid= 12183448 |doi= 10.1074/jbc.M201784200 }}
*{{cite journal  | author=Rappsilber J, Ryder U, Lamond AI, Mann M |title=Large-scale proteomic analysis of the human spliceosome. |journal=Genome Res. |volume=12 |issue= 8 |pages= 1231-45 |year= 2002 |pmid= 12176931 |doi= 10.1101/gr.473902 }}
*{{cite journal  | vauthors=Rappsilber J, Ryder U, Lamond AI, Mann M |title=Large-scale proteomic analysis of the human spliceosome. |journal=Genome Res. |volume=12 |issue= 8 |pages= 1231–45 |year= 2002 |pmid= 12176931 |doi= 10.1101/gr.473902  | pmc=186633 }}
*{{cite journal | author=Zhang DL, Sun XJ, Ling LJ, ''et al.'' |title=[Molecular cloning, characterization, chromosomal assignment, genomic organization and verification of SFRS12(SRrp508), a novel member of human SR protein superfamily and a human homolog of rat SRrp86] |journal=Yi Chuan Xue Bao |volume=29 |issue= 5 |pages= 377-83 |year= 2002 |pmid= 12043562 |doi=  }}
*{{cite journal  | vauthors=Barnard DC, Li J, Peng R, Patton JG |title=Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. |journal=RNA |volume=8 |issue= 4 |pages= 526–33 |year= 2002 |pmid= 11991645 |doi=10.1017/S1355838202029928  | pmc=1370273 }}
*{{cite journal  | author=Barnard DC, Li J, Peng R, Patton JG |title=Regulation of alternative splicing by SRrp86 through coactivation and repression of specific SR proteins. |journal=RNA |volume=8 |issue= 4 |pages= 526-33 |year= 2002 |pmid= 11991645 |doi=  }}
*{{cite journal  | vauthors=Barnard DC, Patton JG |title=Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. |journal=Mol. Cell. Biol. |volume=20 |issue= 9 |pages= 3049–57 |year= 2000 |pmid= 10757789 |doi=10.1128/MCB.20.9.3049-3057.2000  | pmc=85584 }}
*{{cite journal  | author=Barnard DC, Patton JG |title=Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. |journal=Mol. Cell. Biol. |volume=20 |issue= 9 |pages= 3049-57 |year= 2000 |pmid= 10757789 |doi=  }}
}}
}}
{{refend}}
{{refend}}


{{protein-stub}}
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
{{WikiDoc Sources}}
{{PBB_Controls
| update_page = yes
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}
 
 
{{gene-5-stub}}

Latest revision as of 06:13, 11 September 2017

VALUE_ERROR (nil)
Identifiers
Aliases
External IDsGeneCards: [1]
Orthologs
SpeciesHumanMouse
Entrez

n/a

n/a

Ensembl

n/a

n/a

UniProt

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)n/an/a
PubMed searchn/an/a
Wikidata
View/Edit Human

Splicing factor, arginine/serine-rich 12 is a protein that in humans is encoded by the SFRS12 gene.[1][2]

SFRS12 belongs to the superfamily of serine/arginine-rich (SR) splicing factors. It modulates splice site selection by regulating the activities of other SR proteins (Barnard et al., 2002).[supplied by OMIM][2]

References

  1. ↑ Zhang DL, Sun XJ, Ling LJ, Chen RS, Ma DL (Jun 2002). "[Molecular cloning, characterization, chromosomal assignment, genomic organization and verification of SFRS12(SRrp508), a novel member of human SR protein superfamily and a human homolog of rat SRrp86]". Yi Chuan Xue Bao. 29 (5): 377–83. PMID 12043562.
  2. ↑ 2.0 2.1 "Entrez Gene: SFRS12 splicing factor, arginine/serine-rich 12".

Further reading



Retrieved from "https://www.wikidoc.org/index.php?title=SFRS12&oldid=1420451"